Hemodynamic-mediated endocardial signaling controls in vivo myocardial reprogramming

Lower vertebrate and neonatal mammalian hearts exhibit the remarkable capacity to regenerate through the reprogramming of pre-existing cardiomyocytes. However, how cardiac injury initiates signaling pathways controlling this regenerative reprogramming remains to be defined. Here, we utilize in vivo...

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Bibliographic Details

Published in:	eLife
Main Authors:	Manuel Gálvez-Santisteban, Danni Chen, Ruilin Zhang, Ricardo Serrano, Cathleen Nguyen, Long Zhao, Laura Nerb, Evan M Masutani, Julien Vermot, Charles Geoffrey Burns, Caroline E Burns, Juan C del Álamo, Neil C Chi
Format:	Article
Language:	English
Published:	eLife Sciences Publications Ltd 2019-06-01
Subjects:	regeneration heart hemodynamics reprogramming genetics
Online Access:	https://elifesciences.org/articles/44816