The <i>Allium cepa</i> Model: A Review of Its Application as a Cytogenetic Tool for Evaluating the Biosafety Potential of Plant Extracts
In establishing the safety or tolerability profile of bioactive plant extracts, it is important to perform toxicity studies using appropriate, accessible, and sustainable methods. The <i>Allium cepa</i> model is well known and frequently used for accurate environmental risk assessments,...
| Published in: | Methods and Protocols |
|---|---|
| Main Authors: | Daniela Nicuță, Luminița Grosu, Oana-Irina Patriciu, Roxana-Elena Voicu, Irina-Claudia Alexa |
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2025-08-01
|
| Subjects: | |
| Online Access: | https://www.mdpi.com/2409-9279/8/4/88 |
Similar Items
Sustainable Characterization of Some Extracts of <i>Origanum vulgare</i> L. and Biosafety Evaluation Using <i>Allium cepa</i> Assay
by: Daniela Nicuță, et al.
Published: (2024-05-01)
by: Daniela Nicuță, et al.
Published: (2024-05-01)
Evaluation of the cytogenetic and genotoxic effects of an abamectin-based pesticide on Allium cepa roots
by: Ili Pinar, et al.
Published: (2024-01-01)
by: Ili Pinar, et al.
Published: (2024-01-01)
Antioxidant and Immune Stimulating Effects of <i>Allium cepa</i> Skin in the RAW 264.7 Cells and in the C57BL/6 Mouse Immunosuppressed by Cyclophosphamide
by: Ji-Su Kim, et al.
Published: (2023-04-01)
by: Ji-Su Kim, et al.
Published: (2023-04-01)
Bioassays with <i>Allium cepa</i> for the Monitoring of Toxicity in the Groundwater of Yucatan, Mexico
by: Loremy Yehudí Cauich-Suárez, et al.
Published: (2024-12-01)
by: Loremy Yehudí Cauich-Suárez, et al.
Published: (2024-12-01)
Cytogenetic Effects of Radiation from Projector on Meristematic Cells of Allium Cepa (Onions) Root
by: G. O. Alege, et al.
Published: (2022-04-01)
by: G. O. Alege, et al.
Published: (2022-04-01)
Differences in Antioxidant Potential of <i>Allium cepa</i> Husk of Red, Yellow, and White Varieties
by: Irina Chernukha, et al.
Published: (2022-06-01)
by: Irina Chernukha, et al.
Published: (2022-06-01)
Comparative analysis of the complete plastomes of garlic Allium sativum and bulb onion Allium cepa
by: M. A. Filyushin, et al.
Published: (2018-08-01)
by: M. A. Filyushin, et al.
Published: (2018-08-01)
Hospital waste: impact on Allium cepa cells
by: Marcella Schneider Brun Campos, et al.
Published: (2024-06-01)
by: Marcella Schneider Brun Campos, et al.
Published: (2024-06-01)
Effect of low oxygen storage on carbohydrate changes in onion (Allium cepa var. cepa) bulbs
by: M. K. Ernst, et al.
Published: (2003-01-01)
by: M. K. Ernst, et al.
Published: (2003-01-01)
Effect of Ferrous Gluconate on Chromosomal Abnormality Index of Allium Cepa Root Tip
by: Nergis Kaya
Published: (2021-04-01)
by: Nergis Kaya
Published: (2021-04-01)
Onion (<i>Allium cepa</i> L.)-Derived Nanoparticles Inhibited LPS-Induced Nitrate Production, However, Their Intracellular Incorporation by Endocytosis Was Not Involved in This Effect on RAW264 Cells
by: Masao Yamasaki, et al.
Published: (2021-05-01)
by: Masao Yamasaki, et al.
Published: (2021-05-01)
Common onion extract (Allium cepa): radioprotective or radiosensitizing?
by: Raquel Cordeiro de Oliveira, et al.
Published: (2025-09-01)
by: Raquel Cordeiro de Oliveira, et al.
Published: (2025-09-01)
Comparative Metabolomics Profiling of Polyphenols, Nutrients and Antioxidant Activities of Two Red Onion (<i>Allium cepa</i> L.) Cultivars
by: Rita Metrani, et al.
Published: (2020-08-01)
by: Rita Metrani, et al.
Published: (2020-08-01)
Therapeutic Effects of Allium sativum and Allium cepa in Schistosoma mansoni experimental infection
by: Mona Mohamed Mantawy, et al.
Published: (2011-06-01)
by: Mona Mohamed Mantawy, et al.
Published: (2011-06-01)
Prevention and Control of <i>Fusarium</i> spp., the Causal Agents of Onion (<i>Allium cepa</i>) Basal Rot
by: Ofir Degani, et al.
Published: (2022-11-01)
by: Ofir Degani, et al.
Published: (2022-11-01)
Cytogenetic effects of Tribulus terrestris L. on meristematic cells of Allium cepa L. and Vicia faba L.
by: Ali Bouzekri, et al.
Published: (2023-09-01)
by: Ali Bouzekri, et al.
Published: (2023-09-01)
Antioxidant Power on Dermal Cells by Textiles Dyed with an Onion (<i>Allium cepa</i> L.) Skin Extract
by: Claudia Volpi, et al.
Published: (2021-10-01)
by: Claudia Volpi, et al.
Published: (2021-10-01)
Assessment of Commercial Fungicides against Onion (<i>Allium cepa</i>) Basal Rot Disease Caused by <i>Fusarium oxysporum</i> f. sp. <i>cepae</i> and <i>Fusarium acutatum</i>
by: Ofir Degani, et al.
Published: (2021-03-01)
by: Ofir Degani, et al.
Published: (2021-03-01)
Bio-Assay-Guided Isolation of Fractions and Constituents with Antioxidant and Lipid-lowering Activity from <i>Allium cepa</i>
by: Kongming Fan, et al.
Published: (2023-07-01)
by: Kongming Fan, et al.
Published: (2023-07-01)
Combined Toxicity of Methylparaben and Propylparaben in Artemia salina and Allium cepa Applying Experimental Design
by: Estela Moraes Nolasco, et al.
Published: (2023-10-01)
by: Estela Moraes Nolasco, et al.
Published: (2023-10-01)
TLC determination of flavonoids from different cultivars of Allium cepa and Allium ascalonicum
by: Pobłocka-Olech Loretta, et al.
Published: (2016-12-01)
by: Pobłocka-Olech Loretta, et al.
Published: (2016-12-01)
Green Synthesis of Silver Nanoparticles from <i>Allium cepa</i> L. Peel Extract, Their Antioxidant, Antipathogenic, and Anticholinesterase Activity
by: Mehmet Fırat Baran, et al.
Published: (2023-03-01)
by: Mehmet Fırat Baran, et al.
Published: (2023-03-01)
Phytochemical Characterization and Screening of Antioxidant, Antimicrobial and Antiproliferative Properties of <i>Allium × cornutum</i> Clementi and Two Varieties of <i>Allium cepa</i> L. Peel Extracts
by: Željana Fredotović, et al.
Published: (2021-04-01)
by: Željana Fredotović, et al.
Published: (2021-04-01)
Amoebicidal effect of Allium cepa against Allovahlkampfia spelaea: A keratitis model
by: Hanan E.M. Eldeek, et al.
Published: (2022-08-01)
by: Hanan E.M. Eldeek, et al.
Published: (2022-08-01)
Morphological and Molecular Characterization and Life Cycle of <i>Meloidogyne graminicola</i> Infecting <i>Allium cepa</i>
by: Qiankun Li, et al.
Published: (2025-08-01)
by: Qiankun Li, et al.
Published: (2025-08-01)
Responses of the <i>Allium cepa</i> L. to Heavy Metals from Contaminated Soil
by: Ocsana Opriș, et al.
Published: (2024-10-01)
by: Ocsana Opriș, et al.
Published: (2024-10-01)
Protective effect of kavain in meristematic cells of Allium cepa L.
by: ERASMO P. DO VALE JUNIOR, et al.
Published: (2022-06-01)
by: ERASMO P. DO VALE JUNIOR, et al.
Published: (2022-06-01)
Effects of Different Irrigation Regimes and Nitrogen Fertilization on the Physicochemical and Bioactive Characteristics of onion (<i>Allium cepa</i> L.)
by: Susana Marlene Barrales-Heredia, et al.
Published: (2023-03-01)
by: Susana Marlene Barrales-Heredia, et al.
Published: (2023-03-01)
Antioxidant potential and antibacterial activities of Allium cepa (onion) and Allium sativum (garlic) against the multidrug resistance bacteria
by: O. M. Oyawoye, et al.
Published: (2022-07-01)
by: O. M. Oyawoye, et al.
Published: (2022-07-01)
Varietal Differences of Yield, Morphological, and Biochemical Parameters of <i>Allium cepa</i> L. under Precipitation Excess in Different Phenological Phases
by: Nadezhda Golubkina, et al.
Published: (2023-07-01)
by: Nadezhda Golubkina, et al.
Published: (2023-07-01)
Argovit™ Silver Nanoparticles Effects on <i>Allium cepa</i>: Plant Growth Promotion without Cyto Genotoxic Damage
by: Francisco Casillas-Figueroa, et al.
Published: (2020-07-01)
by: Francisco Casillas-Figueroa, et al.
Published: (2020-07-01)
Evaluation of the biosafety potentials of methanol extracts/fractions of Tapinanthus bangwensis and Moringa oleifera leaves using Allium cepa model
by: Godwin O. Ihegboro, et al.
Published: (2020-01-01)
by: Godwin O. Ihegboro, et al.
Published: (2020-01-01)
Comparison of Organosulfur and Amino Acid Composition between Triploid Onion <i>Allium cornutum</i> Clementi ex Visiani, 1842, and Common Onion <i>Allium cepa</i> L., and Evidences for Antiproliferative Activity of Their Extracts
by: Željana Fredotović, et al.
Published: (2020-01-01)
by: Željana Fredotović, et al.
Published: (2020-01-01)
Combined Soil Microorganism Amendments and Foliar Micronutrient Nanofertilization Increased the Production of <i>Allium cepa</i> L. through Aquaporin Gene Regulation
by: José A. Berna-Sicilia, et al.
Published: (2023-12-01)
by: José A. Berna-Sicilia, et al.
Published: (2023-12-01)
Treatment Effects of Onion (Allium cepa) and Ginger
by: Hussein Nikniaz, et al.
Published: (2012-09-01)
by: Hussein Nikniaz, et al.
Published: (2012-09-01)
Beneficial Effects of Organosulfur Compounds from <i>Allium cepa</i> on Gut Health: A Systematic Review
by: Enrique Guillamón, et al.
Published: (2021-07-01)
by: Enrique Guillamón, et al.
Published: (2021-07-01)
Evaluation of the Cytogenotoxic Effects of Emulsifiable Concentrate form of Amitraz Pesticide on <i>Allium cepa</i> L
by: A.A Adesuyi, et al.
Published: (2019-01-01)
by: A.A Adesuyi, et al.
Published: (2019-01-01)
<i>In Vitro</i> Bioaccessibility and Anti-Inflammatory Activity of a Chemically Characterized <i>Allium cepa</i> L. Extract Rich in Quercetin Derivatives Optimized by the Design of Experiments
by: Hammad Ullah, et al.
Published: (2022-12-01)
by: Hammad Ullah, et al.
Published: (2022-12-01)
Effect of aqueous <i>Allium cepa</i> extract from red onion on aluminum chloride- induced anemia in female rats
by: S.F. Ige, et al.
Published: (2018-02-01)
by: S.F. Ige, et al.
Published: (2018-02-01)
<i>Allium</i> Species in the Balkan Region—Major Metabolites, Antioxidant and Antimicrobial Properties
by: Sandra Vuković, et al.
Published: (2023-03-01)
by: Sandra Vuković, et al.
Published: (2023-03-01)
Similar Items
-
Sustainable Characterization of Some Extracts of <i>Origanum vulgare</i> L. and Biosafety Evaluation Using <i>Allium cepa</i> Assay
by: Daniela Nicuță, et al.
Published: (2024-05-01) -
Evaluation of the cytogenetic and genotoxic effects of an abamectin-based pesticide on Allium cepa roots
by: Ili Pinar, et al.
Published: (2024-01-01) -
Antioxidant and Immune Stimulating Effects of <i>Allium cepa</i> Skin in the RAW 264.7 Cells and in the C57BL/6 Mouse Immunosuppressed by Cyclophosphamide
by: Ji-Su Kim, et al.
Published: (2023-04-01) -
Bioassays with <i>Allium cepa</i> for the Monitoring of Toxicity in the Groundwater of Yucatan, Mexico
by: Loremy Yehudí Cauich-Suárez, et al.
Published: (2024-12-01) -
Cytogenetic Effects of Radiation from Projector on Meristematic Cells of Allium Cepa (Onions) Root
by: G. O. Alege, et al.
Published: (2022-04-01)
