Cancer-cell-secreted miR-204-5p induces leptin signalling pathway in white adipose tissue to promote cancer-associated cachexia

Abstract Cancer-associated cachexia is a multi-organ weight loss syndrome, especially with a wasting disorder of adipose tissue and skeletal muscle. Small extracellular vesicles (sEVs) serve as emerging messengers to connect primary tumour and metabolic organs to exert systemic regulation. However,...

وصف كامل

التفاصيل البيبلوغرافية
الحاوية / القاعدة:Nature Communications
المؤلفون الرئيسيون: Yong Hu, Liu Liu, Yong Chen, Xiaohui Zhang, Haifeng Zhou, Sheng Hu, Xu Li, Meixin Li, Juanjuan Li, Siyuan Cheng, Yong Liu, Yancheng Xu, Wei Yan
التنسيق: مقال
اللغة:الإنجليزية
منشور في: Nature Portfolio 2023-08-01
الوصول للمادة أونلاين:https://doi.org/10.1038/s41467-023-40571-9