Mineralization of regenerated cellulose hydrogels induced by human bone marrow stromal cells

The proliferation of cultured human bone marrow stromal cells (HBMSC) on regenerated cellulose hydrogels was assessed. Regenerated cellulose hydrogels showed good rates of HBMSC proliferation, the cells exhibiting a flattened morphology, and after 22 days in culture, the cells had homogeneously colo...

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التفاصيل البيبلوغرافية
الحاوية / القاعدة:European Cells & Materials
المؤلفون الرئيسيون: Granja P. L., De Jéso B., Bareille R., Rouais F., Baquey C., Barbosa M. A.
التنسيق: مقال
اللغة:الإنجليزية
منشور في: Forum Multimedia Publishing LLC 2005-10-01
الوصول للمادة أونلاين:http://www.ecmjournal.org/journal/papers/vol010/vol010a04.php
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author Granja P. L.
De Jéso B.
Bareille R.
Rouais F.
Baquey C.
Barbosa M. A.
author_facet Granja P. L.
De Jéso B.
Bareille R.
Rouais F.
Baquey C.
Barbosa M. A.
author_sort Granja P. L.
collection DOAJ
container_title European Cells & Materials
description The proliferation of cultured human bone marrow stromal cells (HBMSC) on regenerated cellulose hydrogels was assessed. Regenerated cellulose hydrogels showed good rates of HBMSC proliferation, the cells exhibiting a flattened morphology, and after 22 days in culture, the cells had homogeneously colonized the surface of the materials. Moreover, since the early days in culture, between the surface of the materials and attached cells a continuous granulated hydroxyapatite layer was formed. It has been previously demonstrated in vitro, but without cells, that these materials did not mineralize. Hence, it seems that HBMSC promoted the mineralization of the surface.
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spelling doaj-art-316245aff2ec4e0bb73d2ef467402c6f2025-08-19T23:19:04ZengForum Multimedia Publishing LLCEuropean Cells & Materials1473-22622005-10-01103139Mineralization of regenerated cellulose hydrogels induced by human bone marrow stromal cellsGranja P. L.De Jéso B.Bareille R.Rouais F.Baquey C.Barbosa M. A.The proliferation of cultured human bone marrow stromal cells (HBMSC) on regenerated cellulose hydrogels was assessed. Regenerated cellulose hydrogels showed good rates of HBMSC proliferation, the cells exhibiting a flattened morphology, and after 22 days in culture, the cells had homogeneously colonized the surface of the materials. Moreover, since the early days in culture, between the surface of the materials and attached cells a continuous granulated hydroxyapatite layer was formed. It has been previously demonstrated in vitro, but without cells, that these materials did not mineralize. Hence, it seems that HBMSC promoted the mineralization of the surface.http://www.ecmjournal.org/journal/papers/vol010/vol010a04.php
spellingShingle Granja P. L.
De Jéso B.
Bareille R.
Rouais F.
Baquey C.
Barbosa M. A.
Mineralization of regenerated cellulose hydrogels induced by human bone marrow stromal cells
title Mineralization of regenerated cellulose hydrogels induced by human bone marrow stromal cells
title_full Mineralization of regenerated cellulose hydrogels induced by human bone marrow stromal cells
title_fullStr Mineralization of regenerated cellulose hydrogels induced by human bone marrow stromal cells
title_full_unstemmed Mineralization of regenerated cellulose hydrogels induced by human bone marrow stromal cells
title_short Mineralization of regenerated cellulose hydrogels induced by human bone marrow stromal cells
title_sort mineralization of regenerated cellulose hydrogels induced by human bone marrow stromal cells
url http://www.ecmjournal.org/journal/papers/vol010/vol010a04.php
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