Synthetic Routes to Coumarin(Benzopyrone)-Fused Five-Membered Aromatic Heterocycles Built on the α-Pyrone Moiety. Part II: Five-Membered Aromatic Rings with Multi Heteroatoms
Coumarins are natural heterocycles that widely contribute to the design of various biologically active compounds. Fusing different aromatic heterocycles with coumarin at its 3,4-position is one of the interesting approaches to generating novel molecules with various biological activities. During our...
| Published in: | Molecules |
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| Main Authors: | , , |
| Format: | Article |
| Language: | English |
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MDPI AG
2021-06-01
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| Online Access: | https://www.mdpi.com/1420-3049/26/11/3409 |
| _version_ | 1851843369573023744 |
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| author | Eslam Reda El-Sawy Ahmed Bakr Abdelwahab Gilbert Kirsch |
| author_facet | Eslam Reda El-Sawy Ahmed Bakr Abdelwahab Gilbert Kirsch |
| author_sort | Eslam Reda El-Sawy |
| collection | DOAJ |
| container_title | Molecules |
| description | Coumarins are natural heterocycles that widely contribute to the design of various biologically active compounds. Fusing different aromatic heterocycles with coumarin at its 3,4-position is one of the interesting approaches to generating novel molecules with various biological activities. During our continuing interest in assembling information about fused five-membered aromatic heterocycles, and after having presented mono-hetero-atomic five-membered aromatic heterocycles in Part I. The current review Part II is intended to present an overview of the different synthetic routes to coumarin (benzopyrone)-fused five-membered aromatic heterocycles with multi-heteroatoms built on the pyrone ring, covering the literature from 1945 to 2021. |
| format | Article |
| id | doaj-art-3384c2dd5ea74dfbbc772ca84bc4d5a9 |
| institution | Directory of Open Access Journals |
| issn | 1420-3049 |
| language | English |
| publishDate | 2021-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| spelling | doaj-art-3384c2dd5ea74dfbbc772ca84bc4d5a92025-08-19T22:27:23ZengMDPI AGMolecules1420-30492021-06-012611340910.3390/molecules26113409Synthetic Routes to Coumarin(Benzopyrone)-Fused Five-Membered Aromatic Heterocycles Built on the α-Pyrone Moiety. Part II: Five-Membered Aromatic Rings with Multi HeteroatomsEslam Reda El-Sawy0Ahmed Bakr Abdelwahab1Gilbert Kirsch2National Research Centre, Chemistry of Natural Compounds Department, Dokki, Cairo 12622, EgyptPlant Advanced Technologies (PAT), 54500 Vandoeuvre-les-Nancy, FranceLaboratoire Lorrain de Chimie Moléculaire (L.2.C.M.), Université de Lorraine, 57078 Metz, FranceCoumarins are natural heterocycles that widely contribute to the design of various biologically active compounds. Fusing different aromatic heterocycles with coumarin at its 3,4-position is one of the interesting approaches to generating novel molecules with various biological activities. During our continuing interest in assembling information about fused five-membered aromatic heterocycles, and after having presented mono-hetero-atomic five-membered aromatic heterocycles in Part I. The current review Part II is intended to present an overview of the different synthetic routes to coumarin (benzopyrone)-fused five-membered aromatic heterocycles with multi-heteroatoms built on the pyrone ring, covering the literature from 1945 to 2021.https://www.mdpi.com/1420-3049/26/11/3409coumarinsbenzopyronespyrazoleimidazolethiazoleoxazole |
| spellingShingle | Eslam Reda El-Sawy Ahmed Bakr Abdelwahab Gilbert Kirsch Synthetic Routes to Coumarin(Benzopyrone)-Fused Five-Membered Aromatic Heterocycles Built on the α-Pyrone Moiety. Part II: Five-Membered Aromatic Rings with Multi Heteroatoms coumarins benzopyrones pyrazole imidazole thiazole oxazole |
| title | Synthetic Routes to Coumarin(Benzopyrone)-Fused Five-Membered Aromatic Heterocycles Built on the α-Pyrone Moiety. Part II: Five-Membered Aromatic Rings with Multi Heteroatoms |
| title_full | Synthetic Routes to Coumarin(Benzopyrone)-Fused Five-Membered Aromatic Heterocycles Built on the α-Pyrone Moiety. Part II: Five-Membered Aromatic Rings with Multi Heteroatoms |
| title_fullStr | Synthetic Routes to Coumarin(Benzopyrone)-Fused Five-Membered Aromatic Heterocycles Built on the α-Pyrone Moiety. Part II: Five-Membered Aromatic Rings with Multi Heteroatoms |
| title_full_unstemmed | Synthetic Routes to Coumarin(Benzopyrone)-Fused Five-Membered Aromatic Heterocycles Built on the α-Pyrone Moiety. Part II: Five-Membered Aromatic Rings with Multi Heteroatoms |
| title_short | Synthetic Routes to Coumarin(Benzopyrone)-Fused Five-Membered Aromatic Heterocycles Built on the α-Pyrone Moiety. Part II: Five-Membered Aromatic Rings with Multi Heteroatoms |
| title_sort | synthetic routes to coumarin benzopyrone fused five membered aromatic heterocycles built on the α pyrone moiety part ii five membered aromatic rings with multi heteroatoms |
| topic | coumarins benzopyrones pyrazole imidazole thiazole oxazole |
| url | https://www.mdpi.com/1420-3049/26/11/3409 |
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