18F-FDG PET/CT Findings in Cytomegalovirus Colitis

We present a case demonstrating the diagnostic work-up of a patient undergoing azathioprine treatment for inflammatory bowel disease (IBD), diagnosed with an acute cytomegalovirus (CMV) infection and CMV colitis. An 18F-FDG positron emission tomography/computed tomography (PET/CT) performed 2 weeks...

Full description

Bibliographic Details
Published in:Diagnostics
Main Authors: Anna Sophie L. Kjaer, Iben Ribberholt, Kim Thomsen, Per H. Ibsen, Elena Markova, Jesper Graff
Format: Article
Language:English
Published: MDPI AG 2018-12-01
Subjects:
18F-FDG PET/CT
cytomegalovirus colitis
inflammatory bowel disease
Online Access:http://www.mdpi.com/2075-4418/9/1/3
Description
Summary:We present a case demonstrating the diagnostic work-up of a patient undergoing azathioprine treatment for inflammatory bowel disease (IBD), diagnosed with an acute cytomegalovirus (CMV) infection and CMV colitis. An 18F-FDG positron emission tomography/computed tomography (PET/CT) performed 2 weeks after debut of symptoms revealed pathological 18F-FDG uptake in the left side of the colon mucosa, mimicked activity of IBD. However, a diagnosis of CMV colitis was based on the presence of CMV IgM antibodies, a seroconversion of CMV IgG antibodies, presence of CMV DNA in plasma and the finding af CMV DNA in biopsies from the intestinal mucosa. The patient responded to treatment with ganciclovir. This case highlights that a positive 18F-FDG PET/CT scan of the colon can be due to CMV colitis.
ISSN:2075-4418

Similar Items