Revolutionizing Diabetes and Obesity Management: A Comprehensive Review of Tirzepatide’s Dual Agonist Approach

Tirzepatide, an innovative glucagon-like peptide-1 (GLP-1) and glucagon receptor dual agonist, has emerged as a promising therapeutic avenue for type 2 diabetes and obesity management. This review encompasses a comprehensive evaluation of Tirzepatide’s mechanism of action, clinical efficacy, safety...

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Published in:JK Science
Main Authors: Sonam Samal, Sourav Maiti, Jonnalagadda Vihari
Format: Article
Language:English
Published: Dr. Annil Mahajan 2024-04-01
Subjects:
Online Access:https://journal.jkscience.org/index.php/JK-Science/article/view/266
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author Sonam Samal
Sourav Maiti
Jonnalagadda Vihari
author_facet Sonam Samal
Sourav Maiti
Jonnalagadda Vihari
author_sort Sonam Samal
collection DOAJ
container_title JK Science
description Tirzepatide, an innovative glucagon-like peptide-1 (GLP-1) and glucagon receptor dual agonist, has emerged as a promising therapeutic avenue for type 2 diabetes and obesity management. This review encompasses a comprehensive evaluation of Tirzepatide’s mechanism of action, clinical efficacy, safety profile, and comparative effectiveness against existing treatments. By targeting multiple pathways related to glucose and weight regulation, Tirzepatide exhibits superior glycemic control and substantial weight loss, presenting a novel approach to address the intertwined challenges of diabetes and obesity. An analysis of pivotal clinical trials, potential adverse effects, and future directions in Tirzepatide research further underscores its potential as a transformative treatment strategy.
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spelling doaj-art-34d86c4e28fa436fb714d969f8317c382025-08-19T23:28:49ZengDr. Annil MahajanJK Science0972-11772024-04-01262Revolutionizing Diabetes and Obesity Management: A Comprehensive Review of Tirzepatide’s Dual Agonist ApproachSonam SamalSourav MaitiJonnalagadda Vihari Tirzepatide, an innovative glucagon-like peptide-1 (GLP-1) and glucagon receptor dual agonist, has emerged as a promising therapeutic avenue for type 2 diabetes and obesity management. This review encompasses a comprehensive evaluation of Tirzepatide’s mechanism of action, clinical efficacy, safety profile, and comparative effectiveness against existing treatments. By targeting multiple pathways related to glucose and weight regulation, Tirzepatide exhibits superior glycemic control and substantial weight loss, presenting a novel approach to address the intertwined challenges of diabetes and obesity. An analysis of pivotal clinical trials, potential adverse effects, and future directions in Tirzepatide research further underscores its potential as a transformative treatment strategy. https://journal.jkscience.org/index.php/JK-Science/article/view/266TirzepatideGlucagon-like Peptide-1 (GLP-1)Glucagon ReceptorDual AgonistDiabetesObesity
spellingShingle Sonam Samal
Sourav Maiti
Jonnalagadda Vihari
Revolutionizing Diabetes and Obesity Management: A Comprehensive Review of Tirzepatide’s Dual Agonist Approach
Tirzepatide
Glucagon-like Peptide-1 (GLP-1)
Glucagon Receptor
Dual Agonist
Diabetes
Obesity
title Revolutionizing Diabetes and Obesity Management: A Comprehensive Review of Tirzepatide’s Dual Agonist Approach
title_full Revolutionizing Diabetes and Obesity Management: A Comprehensive Review of Tirzepatide’s Dual Agonist Approach
title_fullStr Revolutionizing Diabetes and Obesity Management: A Comprehensive Review of Tirzepatide’s Dual Agonist Approach
title_full_unstemmed Revolutionizing Diabetes and Obesity Management: A Comprehensive Review of Tirzepatide’s Dual Agonist Approach
title_short Revolutionizing Diabetes and Obesity Management: A Comprehensive Review of Tirzepatide’s Dual Agonist Approach
title_sort revolutionizing diabetes and obesity management a comprehensive review of tirzepatide s dual agonist approach
topic Tirzepatide
Glucagon-like Peptide-1 (GLP-1)
Glucagon Receptor
Dual Agonist
Diabetes
Obesity
url https://journal.jkscience.org/index.php/JK-Science/article/view/266
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AT jonnalagaddavihari revolutionizingdiabetesandobesitymanagementacomprehensivereviewoftirzepatidesdualagonistapproach