Revolutionizing Diabetes and Obesity Management: A Comprehensive Review of Tirzepatide’s Dual Agonist Approach
Tirzepatide, an innovative glucagon-like peptide-1 (GLP-1) and glucagon receptor dual agonist, has emerged as a promising therapeutic avenue for type 2 diabetes and obesity management. This review encompasses a comprehensive evaluation of Tirzepatide’s mechanism of action, clinical efficacy, safety...
| Published in: | JK Science |
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| Main Authors: | , , |
| Format: | Article |
| Language: | English |
| Published: |
Dr. Annil Mahajan
2024-04-01
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| Subjects: | |
| Online Access: | https://journal.jkscience.org/index.php/JK-Science/article/view/266 |
| _version_ | 1850307082061873152 |
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| author | Sonam Samal Sourav Maiti Jonnalagadda Vihari |
| author_facet | Sonam Samal Sourav Maiti Jonnalagadda Vihari |
| author_sort | Sonam Samal |
| collection | DOAJ |
| container_title | JK Science |
| description |
Tirzepatide, an innovative glucagon-like peptide-1 (GLP-1) and glucagon receptor dual agonist, has emerged as a promising therapeutic avenue for type 2 diabetes and obesity management. This review encompasses a comprehensive evaluation of Tirzepatide’s mechanism of action, clinical efficacy, safety profile, and comparative effectiveness against existing treatments. By targeting multiple pathways related to glucose and weight regulation, Tirzepatide exhibits superior glycemic control and substantial weight loss, presenting a novel approach to address the intertwined challenges of diabetes and obesity. An analysis of pivotal clinical trials, potential adverse effects, and future directions in Tirzepatide research further underscores its potential as a transformative treatment strategy.
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| format | Article |
| id | doaj-art-34d86c4e28fa436fb714d969f8317c38 |
| institution | Directory of Open Access Journals |
| issn | 0972-1177 |
| language | English |
| publishDate | 2024-04-01 |
| publisher | Dr. Annil Mahajan |
| record_format | Article |
| spelling | doaj-art-34d86c4e28fa436fb714d969f8317c382025-08-19T23:28:49ZengDr. Annil MahajanJK Science0972-11772024-04-01262Revolutionizing Diabetes and Obesity Management: A Comprehensive Review of Tirzepatide’s Dual Agonist ApproachSonam SamalSourav MaitiJonnalagadda Vihari Tirzepatide, an innovative glucagon-like peptide-1 (GLP-1) and glucagon receptor dual agonist, has emerged as a promising therapeutic avenue for type 2 diabetes and obesity management. This review encompasses a comprehensive evaluation of Tirzepatide’s mechanism of action, clinical efficacy, safety profile, and comparative effectiveness against existing treatments. By targeting multiple pathways related to glucose and weight regulation, Tirzepatide exhibits superior glycemic control and substantial weight loss, presenting a novel approach to address the intertwined challenges of diabetes and obesity. An analysis of pivotal clinical trials, potential adverse effects, and future directions in Tirzepatide research further underscores its potential as a transformative treatment strategy. https://journal.jkscience.org/index.php/JK-Science/article/view/266TirzepatideGlucagon-like Peptide-1 (GLP-1)Glucagon ReceptorDual AgonistDiabetesObesity |
| spellingShingle | Sonam Samal Sourav Maiti Jonnalagadda Vihari Revolutionizing Diabetes and Obesity Management: A Comprehensive Review of Tirzepatide’s Dual Agonist Approach Tirzepatide Glucagon-like Peptide-1 (GLP-1) Glucagon Receptor Dual Agonist Diabetes Obesity |
| title | Revolutionizing Diabetes and Obesity Management: A Comprehensive Review of Tirzepatide’s Dual Agonist Approach |
| title_full | Revolutionizing Diabetes and Obesity Management: A Comprehensive Review of Tirzepatide’s Dual Agonist Approach |
| title_fullStr | Revolutionizing Diabetes and Obesity Management: A Comprehensive Review of Tirzepatide’s Dual Agonist Approach |
| title_full_unstemmed | Revolutionizing Diabetes and Obesity Management: A Comprehensive Review of Tirzepatide’s Dual Agonist Approach |
| title_short | Revolutionizing Diabetes and Obesity Management: A Comprehensive Review of Tirzepatide’s Dual Agonist Approach |
| title_sort | revolutionizing diabetes and obesity management a comprehensive review of tirzepatide s dual agonist approach |
| topic | Tirzepatide Glucagon-like Peptide-1 (GLP-1) Glucagon Receptor Dual Agonist Diabetes Obesity |
| url | https://journal.jkscience.org/index.php/JK-Science/article/view/266 |
| work_keys_str_mv | AT sonamsamal revolutionizingdiabetesandobesitymanagementacomprehensivereviewoftirzepatidesdualagonistapproach AT souravmaiti revolutionizingdiabetesandobesitymanagementacomprehensivereviewoftirzepatidesdualagonistapproach AT jonnalagaddavihari revolutionizingdiabetesandobesitymanagementacomprehensivereviewoftirzepatidesdualagonistapproach |
