Overexpression of Mitochondrial Ferritin Enhances Blood–Brain Barrier Integrity Following Ischemic Stroke in Mice by Maintaining Iron Homeostasis in Endothelial Cells

Blood–brain barrier (BBB) breakdown, a characteristic feature of ischemic stroke, contributes to poor patient outcomes. Brain microvascular endothelial cells (BMVECs) are a key component of the BBB and dysfunction or death of these cells following cerebral ischemia reperfusion (I/R) injury can disru...

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Bibliographic Details

Published in:	Antioxidants
Main Authors:	Peina Wang, Qianqian Ren, Mengtong Shi, Yuanyuan Liu, Huiyuan Bai, Yan-Zhong Chang
Format:	Article
Language:	English
Published:	MDPI AG 2022-06-01
Subjects:	blood–brain barrier ischemic stroke mitochondrial ferritin iron endothelial cells
Online Access:	https://www.mdpi.com/2076-3921/11/7/1257