Case Series of End-Stage Liver Disease Patients with Severe Coccidioidomycosis

• 出版年: Journal of Fungi
• 主要な著者: Daniel Ho, Kristen D. Kelley, Satya Dandekar, Stuart H. Cohen, George R. Thompson
• フォーマット: 論文
• 言語: 英語
• 出版事項: MDPI AG 2023-02-01
• 主題: liver disease; hepatitis; <i>Coccidioides</i>; mortality
• オンライン･アクセス: https://www.mdpi.com/2309-608X/9/3/305
• ISSN: 2309-608X

Liver disease causes relative compromise of the host immune system through multiple overlapping mechanisms and is an established risk factor for invasive fungal diseases including candidiasis and cryptococcosis. This immunologic derangement also leads to rapid progression of disease with resultant increases in morbidity and mortality. We describe severe coccidioidomycosis cases in the setting of liver dysfunction. Collaborative multi-center epidemiologic studies should be performed to determine the incidence of severe coccidioidomycosis in patients with concurrent liver disease.