Cellular Senescence and Iron Dyshomeostasis in Alzheimer’s Disease

Iron dyshomeostasis is a feature of Alzheimer’s disease (AD). The impact of iron on AD is attributed to its interactions with the central proteins of AD pathology (amyloid precursor protein and tau) and/or through the iron-mediated generation of prooxidant molecules (e.g., hydroxyl radical...

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Bibliographic Details
Published in:	Pharmaceuticals
Main Authors:	Shashank Masaldan, Abdel Ali Belaidi, Scott Ayton, Ashley I. Bush
Format:	Article
Language:	English
Published:	MDPI AG 2019-06-01
Subjects:	Alzheimer’s disease iron homeostasis ferroptosis senescence chelators
Online Access:	https://www.mdpi.com/1424-8247/12/2/93

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