The combination of apatinib and antigen-specific DC-induced T cells exert antitumor effects by potently improving the immune microenvironment of osteosarcoma

Objective: Osteosarcoma (OS) is the most common primary bone sarcoma with a high propensity for local invasion and metastasis. Although the antitumor effect of apatinib has been well confirmed in advanced OS, the synergistic effect of apatinib and immunotherapies has not yet been elucidated. Methods...

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Bibliographic Details

Published in:	Heliyon
Main Authors:	Tu Hu, Wei Sun, Yongjia Jin, Yan Dong, Wanlin Liu, Zhengwang Sun, Yang Xiang, Yong Chen
Format:	Article
Language:	English
Published:	Elsevier 2024-08-01
Subjects:	Osteosarcoma Apatinib DC-T MDSC TAM Immunity
Online Access:	http://www.sciencedirect.com/science/article/pii/S2405844024120476