SAPHO syndrome with a purely osteolytic form: A case report

• 发表在: Radiology Case Reports
• Main Authors: Akira Kakiuchi, MD, Yayoi Yamamoto, MD, PhD, Akira Kanbe, MD, Daichi Kojima, MD, Ayako Hino, MD, PhD, Ayumi Horikawa, MD, PhD, Tsunehiro Doiuchi, MD, Hiroaki Kurihara, MD, PhD
• 格式: 文件
• 语言: 英语
• 出版: Elsevier 2023-10-01
• 主题: SAPHO syndrome; Osteitis
• 在线阅读: http://www.sciencedirect.com/science/article/pii/S193004332300479X
• ISSN: 1930-0433

SAPHO (synovitis, acne, pustulosis, hyperostosis, and osteitis) syndrome is a rare, chronic autoinflammatory disorder that can present with a constellation of cutaneous and osteoarticular symptoms. Osteodestructive lesions are not pathognomonic, whereas hyperostosis and osteitis are the most prominent imaging findings. We report the case of a man with osteolytic changes of the lumbar vertebra and a history of palmoplantar pustulosis. Biopsy revealed no neoplasm, suggesting SAPHO syndrome. Our case demonstrates that knowledge of atypical radiologic findings is necessary for the diagnosis of SAPHO syndrome.