Radiologic evolution of biopsy-proven acute interstitial nephritis: a multimodal imaging case report
This report presents radiologic changes after clinical improvement in a patient with acute interstitial nephritis (AIN). A 45-year-old female patient was referred for decreased renal function. Eight months prior, she had undergone hysterectomy and received chemotherapy. At the start of chemotherapy,...
| Published in: | Kosin Medical Journal |
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| Main Authors: | , , , , , , |
| Format: | Article |
| Language: | English |
| Published: |
Kosin University College of Medicine
2025-03-01
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| Subjects: | |
| Online Access: | http://www.kosinmedj.org/upload/pdf/kmj-25-104.pdf |
| Summary: | This report presents radiologic changes after clinical improvement in a patient with acute interstitial nephritis (AIN). A 45-year-old female patient was referred for decreased renal function. Eight months prior, she had undergone hysterectomy and received chemotherapy. At the start of chemotherapy, her baseline creatinine level was 0.55 mg/dL, which rose to 1.46 mg/dL. Multiple imaging modalities performed when decreased renal function was observed revealed bilateral renal enlargement with increased cortical attenuation on computed tomography (CT), cortical hyperechogenicity on ultrasonography, and diffusion restriction in the renal cortices on magnetic resonance imaging. A renal biopsy was performed, and AIN was diagnosed. Follow-up laboratory tests showed that kidney function had improved to normal levels, and CT at that time showed a reduction in the size of both kidneys. Radiologic changes can serve as clues for the diagnosis of AIN. This is the first report to confirm radiological changes after the clinical improvement of AIN, thereby providing novel information about the course of AIN. |
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| ISSN: | 2005-9531 2586-7024 |