Protein Thermal Stability Changes Induced by the Global Methylation Inhibitor 3-Deazaneplanocin A (DZNep)

DZNep (3-deazaneplanocin A) is commonly used to reduce lysine methylation. DZNep inhibits S-adenosyl-<span style="font-variant: small-caps;">l</span>-homocysteine hydrolase (AHCY), preventing the conversion of S-adenosyl-<span style="font-variant: small-caps;">l...

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Bibliographic Details

Published in:	Biomolecules
Main Authors:	Christine A. Berryhill, Emma H. Doud, Jocelyne N. Hanquier, Whitney R. Smith-Kinnaman, Devon L. McCourry, Amber L. Mosley, Evan M. Cornett
Format:	Article
Language:	English
Published:	MDPI AG 2024-07-01
Subjects:	lysine methylation S-adenosyl-<span style="font-variant: small-caps">l</span>-methionine methionine cycle proteome integral stability alteration assay
Online Access:	https://www.mdpi.com/2218-273X/14/7/817