Pfcrt and pfmdr1 alleles associated with chloroquine resistance in Plasmodium falciparum from Guyana, South America

Using DNA extracted from 112 parasitised blood blots, we screened for the population marker of chloroquine resistance (CQR) pfcrt K76T in Plasmodium falciparum infections from Guyana. Pfmdr1 mutations S1034C, N1042D, and D1246Y also associated with CQR were surveyed as well in 15 isolates for which...

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Bibliographic Details
Published in:	Memorias do Instituto Oswaldo Cruz
Main Authors:	Wallis Best Plummer, Lexley M Pinto Pereira, Christine VF Carrington
Format:	Article
Language:	English
Published:	Fundação Oswaldo Cruz (FIOCRUZ) 2004-06-01
Subjects:	Plasmodium falciparum chloroquine pfmdr1 pfcrt Guyana
Online Access:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762004000400008

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