Research progress of Septin9 and its methylation in malignant tumors

Septin9 is a member of the cytoskeletal GTPase conserved family and is involved in a variety of biological processes. Many studies have shown that Septin9 is related to the occurrence and development of many malignant tumors. The methylated Septin9 gene can be used as a marker for early screening, d...

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Bibliographic Details
Published in:生物医学转化
Main Authors: Zhang Jiaxing, Li Yumin
Format: Article
Language:Chinese
Published: Lanzhou University Press 2021-12-01
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Online Access:http://swyxzh.ijournals.cn/swyxzh/article/html/20210406?st=article_issue
Description
Summary:Septin9 is a member of the cytoskeletal GTPase conserved family and is involved in a variety of biological processes. Many studies have shown that Septin9 is related to the occurrence and development of many malignant tumors. The methylated Septin9 gene can be used as a marker for early screening, diagnosis and prognosis of some malignant tumors, and may become a new target for anticancer therapy. This article reviewed the research progress of Septin9 gene and its methylation in common malignant tumors.
ISSN:2096-8965