Blocking the CD39/CD73 pathway synergizes with anti-CD20 bispecific antibody in nodal B-cell lymphoma

Bispecific antibodies (BsAb) have emerged as a leading treatment modality in patients suffering from B-cell non-Hodgkin’s lymphoma (B-NHL). However, treatment failure is common and may potentially be attributed to pre-existing or emerging T-cell exhaustion. CD39 catalyzes—together with CD73—the hydr...

詳細記述

書誌詳細
出版年:Journal for ImmunoTherapy of Cancer
主要な著者: Carsten Müller-Tidow, Peter Dreger, Joseph Kauer, Wolfgang Huber, Clara Kolbe, Berit Brinkmann, Sascha Dietrich, Tobias Roider
フォーマット: 論文
言語:英語
出版事項: BMJ Publishing Group 2025-01-01
オンライン・アクセス:https://jitc.bmj.com/content/13/1/e009245.full