Intranasal Rapamycin Rescues Mice from Staphylococcal Enterotoxin B-Induced Shock

Staphylococcal enterotoxin B (SEB) and related exotoxins produced by Staphylococcus aureus are potent activators of the immune system and cause toxic shock in humans. Currently there is no effective treatment except for the use of intravenous immunoglobulins administered shortly after SEB exposure....

Full description

Bibliographic Details
Published in:	Toxins
Main Authors:	Teresa Krakauer, Marilyn Buckley
Format:	Article
Language:	English
Published:	MDPI AG 2012-09-01
Subjects:	intranasal rapamycin staphylococcal enterotoxin B shock
Online Access:	http://www.mdpi.com/2072-6651/4/9/718

Similar Items

The Systemic and Pulmonary Immune Response to Staphylococcal Enterotoxins
by: Anthony T. Vella, et al.
Published: (2010-07-01)

Artificial intelligence enhanced electrochemical immunoassay for staphylococcal enterotoxin B
by: Yuliang Zhao, et al.
Published: (2025-06-01)

Staphylococcal Enterotoxin C Is an Important Virulence Factor for Mastitis
by: Rendong Fang, et al.
Published: (2019-03-01)

Rat Model of Staphylococcal Enterotoxin B-Induced Rhinosinusitis
by: Seong-Ki Ahn, et al.
Published: (2008-03-01)

Differences Between Pediatric and Adult T Cell Responses to In Vitro Staphylococcal Enterotoxin B Stimulation
by: Mark E. Rudolph, et al.
Published: (2018-03-01)

Determination of staphylococcal enterotoxins in cheese by immunoenzyme assays
by: Janković Vesna, et al.
Published: (2012-01-01)

Kadar Interleukin-18 pada Kultur Limfosit Penderita Dermatitis Atopik yang Distimulasi Staphylococcal Enterotoxin B (SEB)
by: Oki Suwarsa, et al.
Published: (2015-12-01)

Effect of (−)-Epigallocatechin Gallate to Staphylococcal Enterotoxin A on Toxin Activity
by: Yuko Shimamura, et al.
Published: (2020-04-01)

Cellular immune response of Staphylococcus aureus enterotoxin B in Balb/c mice through intranasal infection
by: Hidayatun Nisa Purwanasari, et al.
Published: (2022-07-01)

Staphylococcal Enterotoxins: Description and Importance in Food
by: Mirian Yuliza Rubio Cieza, et al.
Published: (2024-08-01)

First Report of Food Poisoning Due to Staphylococcal Enterotoxin Type B in Döner Kebab (Italy)
by: Angelo Romano, et al.
Published: (2023-09-01)

Development of Nanobody-Based Sandwich ELISA Resistant to SpA Interference for Sensitive Detection of Staphylococcal Enterotoxin A
by: Chenghao Hu, et al.
Published: (2025-10-01)

Staphylococcal Enterotoxins Enhance Biofilm Formation by <i>Staphylococcus aureus</i> in Platelet Concentrates
by: Sylvia Ighem Chi, et al.
Published: (2022-12-01)

Microcalorimetric Investigations of Reversible Staphylococcal Enterotoxin Unfolding
by: Susan C. Berry, et al.
Published: (2022-08-01)

Alternative to Animal Use for Detecting Biologically Active Staphylococcal Enterotoxin Type A
by: Reuven Rasooly, et al.
Published: (2018-12-01)

Prenatal exposure of rats to staphylococcal enterotoxin B alters the expression of Th1 and Th2 cytokines via decreased methylation in the spleen of adult but not neonatal offspring
by: Jing Sun, et al.
Published: (2022-03-01)

Molecular detection of some Staphylococcal enterotoxins in the meat of slaughtered animals in abattoirs, Mosul- Iraq
by: Rana M. Dawood, et al.
Published: (2025-07-01)

Staphylococcal Enterotoxin A Detection from Rheumatoid Arthritis Patients’ Blood and Synovial Fluid
by: Ramezan Ali Ataee, et al.
Published: (2016-02-01)

Characterization of non-classical staphylococcal enterotoxins SElJ and SElW: Biological activities and stability
by: Hisaya K. Ono, et al.
Published: (2025-09-01)

Human Leukemia T-Cell Lines as Alternatives to Animal Use for Detecting Biologically Active Staphylococcal Enterotoxin Type B
by: Reuven Rasooly, et al.
Published: (2021-04-01)

Detection of staphylococcal enterotoxins A and B in cow milk using antigen capture enzyme-linked immunosorbent assay and dot-blot assays
by: Hidayatun Nisa Purwanasari, et al.
Published: (2025-03-01)

Paraben exposure related to Staphylococcal enterotoxin IgE sensitization, allergic rhinitis and nasal patency in children
by: Eun Kyo Ha, et al.
Published: (2025-02-01)

Development of antibodies against recombinant staphylococcal enterotoxin B from food poisoning cases
by: Hidayatun Nisa Purwanasari, et al.
Published: (2024-01-01)

Development of an Immunoassay for Detection of Staphylococcal Enterotoxin-Like J, A Non-Characterized Toxin
by: Hisaya K. Ono, et al.
Published: (2018-11-01)

Coordination of prophage and global regulator leads to high enterotoxin production in staphylococcal food poisoning-associated lineage
by: Yusuke Sato'o, et al.
Published: (2024-03-01)

mRNA-based platform for preventing and treating Staphylococcus aureus by targeted staphylococcal enterotoxin B
by: Fumei Luo, et al.
Published: (2024-11-01)

A Metal Organic Framework-Based Light Scattering ELISA for the Detection of Staphylococcal Enterotoxin B
by: Kai Mao, et al.
Published: (2023-08-01)

Regulation of Staphylococcal Enterotoxin-Induced Inflammation in Spleen Cells from Diabetic Mice by Polyphenols
by: Yuko Shimamura, et al.
Published: (2023-04-01)

Effect of (−)-Epigallocatechin Gallate on Activation of JAK/STAT Signaling Pathway by Staphylococcal Enterotoxin A
by: Yuko Shimamura, et al.
Published: (2021-08-01)

Highly Sensitive and Specific Detection of Staphylococcal Enterotoxins SEA, SEG, SEH, and SEI by Immunoassay
by: Cécile Féraudet Tarisse, et al.
Published: (2021-02-01)

Enterotoxins A and B produced by Staphylococcus aureus increase cell proliferation, invasion and cytarabine resistance in acute myeloid leukemia cell lines
by: Seyhan Turk, et al.
Published: (2023-09-01)

Organization and ELISA-Based Results of the First Proficiency Testing to Evaluate the Ability of European Union Laboratories to Detect Staphylococcal Enterotoxin Type B (SEB) in Buffer and Milk
by: Yacine Nia, et al.
Published: (2016-09-01)

Biosafe Control of Staphylococcal Enterotoxins Production in Shelf-Stable Bacon
by: Carlos Alberto Guerra, et al.
Published: (2025-09-01)

Purification of Staphylococcal Enterotoxin B from local isolates and evaluation of its effect on stomach and small intestine tissue
by: khadija hamad, et al.
Published: (2024-12-01)

Temperature-Induced Unfolding Pathway of Staphylococcal Enterotoxin B: Insights from Circular Dichroism and Molecular Dynamics Simulation
by: LIU Ji, ZHANG Shiyu, ZENG Yu, DENG Yi
Published: (2024-09-01)

Staphylococcal superantigens in colonization and disease
by: Stacey X Xu, et al.
Published: (2012-04-01)

Overexpression of Metastatic Related MicroRNAs, Mir-335 and Mir-10b, by Staphylococcal Enterotoxin B in the Metastatic Breast Cancer Cell Line
by: Mohammad Foad Heidary, et al.
Published: (2015-06-01)

Modeling for Predicting the Time to Detection of Staphylococcal Enterotoxin A in Cooked Chicken Product
by: Jieyun Hu, et al.
Published: (2018-07-01)

Further Evidence for Staphylococcal Food Poisoning Outbreaks Caused by egc-Encoded Enterotoxins
by: Sophia Johler, et al.
Published: (2015-03-01)

Staphylococcal enterotoxins in the Etiopathogenesis of Mucosal Autoimmunity within the Gastrointestinal Tract
by: MaryAnn Principato, et al.
Published: (2014-04-01)