Modified dosing schedule efficacy of fosmidomycin and clindamycin against murine malaria Plasmodium berghei

Fosmidomycin and clindamycin target the Plasmodium apicoplast. Combination clinical trials have produced mixed results with the primary problem being the recrudescent infection frequency by day 28. Given that antibiotic efficacy against bacterial infections often depends on the constant drug presenc...

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Bibliographic Details
Published in:	International Journal for Parasitology: Drugs and Drug Resistance
Main Authors:	Leah A. Walker, Vision Bagonza, Bryce Bobb, David J. Sullivan
Format:	Article
Language:	English
Published:	Elsevier 2025-04-01
Subjects:	Clindamycin Fosmidomycin Pharmacodynamics Apicoplast Murine malaria Plasmodium berghei
Online Access:	http://www.sciencedirect.com/science/article/pii/S2211320724000587

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