Serotype Distribution and Disease Severity in Adults Hospitalized with Streptococcus pneumoniae Infection, Bristol and Bath, UK, 2006‒2022

Ongoing surveillance after pneumococcal conjugate vaccination (PCV) deployment is essential to inform policy decisions and monitor serotype replacement. We report serotype and disease severity trends in 3,719 adults hospitalized for pneumococcal disease in Bristol and Bath, United Kingdom, during...

Full description

Bibliographic Details
Published in:	Emerging Infectious Diseases
Main Authors:	Catherine Hyams, Robert Challen, David Hettle, Zahin Amin-Chowdhury, Charli Grimes, Gabriella Ruffino, Rauri Conway, Robyn Heath, Paul North, Adam Malin, Nick A. Maskell, Philip Williams, O. Martin Williams, Shamez N. Ladhani, Leon Danon, Adam Finn
Format:	Article
Language:	English
Published:	Centers for Disease Control and Prevention 2023-10-01
Subjects:	pneumonia Streptococcus pneumoniae bacteria pneumococcus serotypes serotype distribution
Online Access:	https://wwwnc.cdc.gov/eid/article/29/10/23-0519_article

Similar Items

Trends in invasive and non-invasive Streptococcus pneumoniae disease in adults hospitalised in Bristol and Bath: a retrospective cohort study, 2006–2022
by: Robert Challen, et al.
Published: (2026-03-01)

Streptococcus Pneumoniae septic arthritis in adults in Bristol and Bath, United Kingdom, 2006–2018: a 13-year retrospective observational cohort study
by: Catherine Hyams, et al.
Published: (2021-01-01)

Distribution of Streptococcus pneumoniae serotypes in the northeast macro-region of São Paulo state/Brazil after the introduction of conjugate vaccine
by: Marta Inês Cazentini Medeiros, et al.
Published: (2017-08-01)

Adult non-invasive pneumococcal pneumonia in Portugal is dominated by serotype 3 and non-PCV13 serotypes 3-years after near universal PCV13 use in children
by: Catarina Silva-Costa, et al.
Published: (2023-12-01)

The serotype-specific prevalence of pneumococci in hospitalized pneumonia patients with COPD: a prospective, multi-center, cohort study
by: Jae Yeol Kim, et al.
Published: (2023-09-01)

Impact of PCV10 on pediatric pneumococcal disease burden in Brazil: time for new recommendations?
by: Daniel Jarovsky, et al.
Published: (2023-03-01)

Variants of Streptococcus pneumoniae Serotype 14 from Papua New Guinea with the Potential to Be Mistyped and Escape Vaccine-Induced Protection
by: Sam Manna, et al.
Published: (2022-08-01)

Streptococcus pneumoniae serotype distribution in Vojvodina before the introduction of pneumococcal conjugate vaccines into the national immunization program
by: Petrović Vladimir, et al.
Published: (2016-01-01)

Parapneumonic effusions related to Streptococcus pneumoniae: serotype and disease severity trends from 2006 to 2018 in Bristol, UK
by: Nick Maskell, et al.
Published: (2023-07-01)

Pneumococcal Polysaccharide Conjugated Vaccines and the Problem of Changing Circulating Serotypes of Pneumococcus
by: N. N. Kostyukova, et al.
Published: (2023-11-01)

SEROTYPE-INDEPENDENT VACCINES AGAINST PNEUMOCOCCAL INFECTION
by: I. B. Semenova, et al.
Published: (2016-08-01)

Etiological role and molecular-genetic features of <i>Streptococcus pneumoniae</i> in children’s infectious diseases
by: I. N. Protasova, et al.
Published: (2020-03-01)

A spitting image: molecular diagnostics applied to saliva enhance detection of Streptococcus pneumoniae and pneumococcal serotype carriage
by: Willem R. Miellet, et al.
Published: (2023-04-01)

Current status and future directions of invasive pneumococcal diseases and prophylactic approaches to control them
by: Paeton L. Wantuch, et al.
Published: (2018-09-01)

Urinary pneumococcal serotype detection among children with and without community-acquired pneumonia
by: Lilliam Ambroggio, et al.
Published: (2025-08-01)

Whole genome sequencing of Streptococcus pneumoniae: development, evaluation and verification of targets for serogroup and serotype prediction using an automated pipeline
by: Georgia Kapatai, et al.
Published: (2016-09-01)

Changes in serotype distribution of <i>Streptococcus pneumonia</i> circulating among children in the Russian Federation after 13-valent pneumococcal conjugate vaccine introduction.
by: S. V. Sidorenko, et al.
Published: (2023-07-01)

GENETIC SURVEY OF INVASIVE S. PNEUMONIAE SEROTYPES IN BULGARIA FOR A 5-YEAR PERIOD
by: Ivan Simeonovski, et al.
Published: (2018-12-01)

Identification of pneumococcal serotypes with individual recognition of vaccine types by a highly multiplexed real-time PCR-based MeltArray approach
by: Shujuan Zhou, et al.
Published: (2024-02-01)

Serotyping and molecular profiles of virulence‐associated genes among Klebsiella pneumoniae isolates from teaching hospitals of Ardabil, Iran: A cross‐sectional study
by: Neda Same Maleki, et al.
Published: (2023-09-01)

Invasive pneumococcal disease in relation to vaccine type serotypes
by: Paeton L. Wantuch, et al.
Published: (2019-04-01)

SEROTYPES AND ANTIMICROBIAL SUSCEPTIBILITY OF NASOPHARYNGEAL PNEUMOCOCCI ISOLATED FROM CHILDREN IN 2010–2016: A RETROSPECTIVE COHORT STUDY
by: Nikolay A. Mayanskiy, et al.
Published: (2017-11-01)

Serotype distribution and antibiotic resistance of Streptococcus pneumoniae isolates collected from unvaccinated children with pneumonia at a province in central Vietnam
by: Bui Anh Son, et al.
Published: (2022-10-01)

Streptococcus pneumoniae serotype 33H: a novel serotype with frameshift mutations in the acetyltransferase gene wciG
by: Sam Manna, et al.
Published: (2025-03-01)

MOLECULAR TYPING OF STREPTOCOCCUS PNEUMONIAE BY THE MULTIPLEX POLYMERASE CHAIN REACTION ASSAY IN ACCORDANCE TO THE PREVALENCE OF SEROTYPES IN THE RUSSIAN FEDERATION
by: N. M. Alyab'eva, et al.
Published: (2013-12-01)

STREPTOCOCCUS PNEUMONIAE MOLECULAR EPIDEMIOLOGICAL FEATURES IN CHILDREN OF KRASNOYARSK REGION
by: I. N. Protasova, et al.
Published: (2014-10-01)

Streptococcus pneumoniae serotype distribution in Bangladeshi under-fives with community-acquired pneumonia pre-10-valent pneumococcal conjugate vaccination
by: Stefan M. T. Vestjens, et al.
Published: (2024-11-01)

Development and evaluation of a novel vaccine against prevalent invasive multi-drug resistant strains of Streptococcus pneumoniae
by: Rehab H. Bahy, et al.
Published: (2016-11-01)

STREPTOCOCCUS PNEUMONIAE SEROTYPE DISTRIBUTION AFTER THE INTRODUCTION OF PNEUMOCOCCAL CONJUGATE VACCINES
by: Mariya Malcheva
Published: (2019-06-01)

A 20-Year Study of Capsular Polysaccharide Seroepidemiology, Susceptibility Profiles, and Virulence Determinants of Klebsiella pneumoniae from Bacteremia Patients in Taiwan
by: Chun-Chou Tsai, et al.
Published: (2023-06-01)

Pediatric case of septic arthritis due to Streptococcus pneumoniae serotype 19A
by: Preslava M. Hristova, et al.
Published: (2023-03-01)

Virulence among different types of hypervirulent Klebsiella pneumoniae with multi-locus sequence type (MLST)-11, Serotype K1 or K2 strains
by: Tsui-Chin Wang, et al.
Published: (2021-06-01)

ANTIMICROBIAL SUSCEPTIBILITY OF S. PNEUMONIAE STRAINS ISOLATED FROM CHILDREN WITH NASOPHARYNGEAL CARRIAGE
by: Mariya Malcheva, et al.
Published: (2020-05-01)

CLINICAL AND BACTERIOLOGICAL PECULIARITIES OF THE ACUTE OTITES MEDIA IN CHILDREN OF 0–5 YEARS OF AGE: PROVISIONAL DATA
by: A. L. Perova, et al.
Published: (2012-10-01)

Pneumococcal carriage among young children attending daycare in Hungary, 12–13 years post-PCV13: a cross-sectional study
by: Andrea Horváth, et al.
Published: (2025-07-01)

Regional Features of the Serotype Composition of Streptococcus pneumoniae isolated from Bacterial Carriers of Preschool Age in the Republic of Tatarstan
by: G. G. Isaeva, et al.
Published: (2023-07-01)

Meningitis-associated pneumococcal serotype 8, ST 53, strain is hypervirulent in a rat model and has non-haemolytic pneumolysin which can be attenuated by liposomes
by: Annelies Müller, et al.
Published: (2023-01-01)

Comparative genomic analysis of two ST320 Streptococcus pneumoniae isolates, representing serotypes 19A and 19F
by: Weronika Puzia, et al.
Published: (2023-04-01)

Streptococcus pneumoniae Serotype 15A in Psychiatric Unit, Rhode Island, USA, 2010–2011
by: Katherine Fleming-Dutra, et al.
Published: (2012-11-01)

Systematic review on serotypes distribution of pneumococcal pneumonia in adults and the elderly
by: Fatiha Mrabt, et al.
Published: (2025-03-01)