TDP-43 as a potential biomarker for amyotrophic lateral sclerosis: a systematic review and meta-analysis

Abstract Background Frontotemporal dementia (FTD) and Amyotrophic Lateral Sclerosis (ALS) are incurable, progressive and fatal neurodegenerative diseases with patients variably affected clinically by motor, behavior, and cognitive deficits. The accumulation of an RNA-binding protein, TDP-43, is the...

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Bibliographic Details
Published in:	BMC Neurology
Main Authors:	Vivek Majumder, Jenna M. Gregory, Marcelo A. Barria, Alison Green, Suvankar Pal
Format:	Article
Language:	English
Published:	BMC 2018-06-01
Subjects:	TDP-43 Amyotrophic lateral sclerosis Biomarker Systematic review Meta-analysis
Online Access:	http://link.springer.com/article/10.1186/s12883-018-1091-7

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