Immune checkpoint inhibitors combined with or without radio(chemo)therapy for locally advanced or recurrent/metastatic esophageal squamous cell carcinoma

Abstract Objective This study was designed to investigate the efficacy and prognostic factors for immune checkpoint inhibitors (ICIs) combined with or without radio(chemo)therapy and to evaluate their toxicity in patients with locally advanced or recurrent/metastatic esophageal squamous cell carcino...

Full description

Bibliographic Details
Published in:	Discover Oncology
Main Authors:	Xiao-Han Zhao, Hong-Mei Gao, Jing-Yuan Wen, He-Song Wang, Luan-Ying Wu, Chun-Yang Song, Wen-Zhao Deng, Shu-Chai Zhu, Wen-Bin Shen
Format:	Article
Language:	English
Published:	Springer 2023-09-01
Subjects:	Immunotherapy Radiotherapy Chemotherapy Esophageal squamous cell carcinoma Prognosis Treatment-related adverse events
Online Access:	https://doi.org/10.1007/s12672-023-00783-3

Similar Items

Chemo-immunotherapy sequential with radiotherapy in advanced or metastatic esophageal squamous cell carcinoma
by: Xiang Han, et al.
Published: (2025-12-01)

The value of intervention with radiotherapy after first-line chemo-immunotherapy in locally advanced or metastatic esophageal squamous cell carcinoma: A multi-center retrospective study
by: Hui-Hui Hu, et al.
Published: (2024-09-01)

Real-world study of first-line immunotherapy combined with chemoradiotherapy in esophageal squamous cell carcinoma
by: Xiaohan Zhao, et al.
Published: (2025-08-01)

Effectiveness of chemotherapy with/without radiotherapy for stage IVb esophageal squamous cell carcinoma: a population-based target trial emulation study
by: Yao-Hung Kuo, et al.
Published: (2025-05-01)

Impact of first-line chemoimmunotherapy with or without radiotherapy on the prognosis of patients with locally advanced or metastatic esophageal squamous cell carcinoma: a multicenter, real-world, retrospective cohort study from China (NCT06478355)
by: Xinyi Liu, et al.
Published: (2025-07-01)

Radiotherapy and chemoradiotherapy for postoperative recurrence in patients with esophageal squamous cell carcinoma
by: Qing Liu, et al.
Published: (2024-08-01)

Radiotherapy combined with immune checkpoint inhibitors in locally advanced/metastatic esophageal squamous cell carcinoma: clinical trials, efficacy and future directions
by: Mengjie Jiang, et al.
Published: (2023-05-01)

Paclitaxel and cisplatin with or without cetuximab in metastatic esophageal squamous cell carcinoma: a randomized, multicenter phase II trial
by: Zhihao Lu, et al.
Published: (2022-05-01)

Dual Targeting of Inflammatory and Immune Checkpoint Pathways to Overcome Radiotherapy Resistance in Esophageal Squamous Cell Carcinoma
by: Qu Z, et al.
Published: (2025-07-01)

Current and future on definitive concurrent chemoradiotherapy for inoperable locally advanced esophageal squamous cell carcinoma
by: Renxian Xie, et al.
Published: (2024-01-01)

Efficacy and safety of camrelizumab combined with chemotherapy as second-line treatment for locally advanced, recurrent, or metastatic esophageal squamous cell carcinoma
by: Yinfang Gu, et al.
Published: (2025-02-01)

Cytomegalovirus reactivation in esophageal cancer patients receiving chemoradiotherapy: A retrospective analysis
by: Koichi Kitagawa, et al.
Published: (2021-11-01)

Concurrent chemoradiotherapy combined with enteral nutrition support: a radical treatment strategy for esophageal squamous cell carcinoma patients with malignant fistulae
by: Li Ma, et al.
Published: (2017-01-01)

Clinical Efficacy of Anlotinib Combined with Paclitaxel and Cisplatin as First-line Treatment of Advanced Esophageal Squamous Cell Carcinoma
by: YANG Xiaoli, et al.
Published: (2021-07-01)

Efficacy of local radiotherapy in first-line treatment of recurrent or metastatic esophageal squamous cell carcinoma based on immunotherapy
by: Dandan Yu, et al.
Published: (2025-10-01)

The treatment outcome of definitive chemoradiotherapy in patients with esophageal squamous cell carcinoma
by: Mahdi Seilanian Toosi, et al.
Published: (2007-10-01)

Clinical efficacy of different neoadjuvant therapies for resectable esophageal squamous cell carcinoma
by: Xiaoyang Wang, et al.
Published: (2025-06-01)

Neoadjuvant versus adjuvant treatment: which one is better for resectable esophageal squamous cell carcinoma?
by: Xu Yaping, et al.
Published: (2012-08-01)

Prognostic factors for esophageal respiratory fistula in unresectable esophageal squamous cell carcinoma treated with radiotherapy
by: Jia-Chao Qi, et al.
Published: (2024-07-01)

Chemoradiotherapy Versus Chemotherapy Alone for Advanced Esophageal Squamous Cell Carcinoma: The Role of Definitive Radiotherapy for Primary Tumor in the Metastatic Setting
by: Li-Qing Li, et al.
Published: (2022-03-01)

Prognostic value of tumor length and diameter for esophageal squamous cell cancer patients treated with definitive (chemo)radiotherapy: Potential indicators for nonsurgical T staging
by: Hongyao Xu, et al.
Published: (2019-10-01)

Sequential boost of intensity‐modulated radiotherapy with chemotherapy for inoperable esophageal squamous cell carcinoma: A prospective phase II study
by: Xing‐Wen Fan, et al.
Published: (2020-04-01)

Preoperative radiotherapy in patients with locally advanced esophageal squamous cell carcinoma: a narrative review
by: Yan Lin, et al.
Published: (2025-07-01)

Real-world clinical impact of first-line immune checkpoint inhibitor-based therapy in advanced esophageal squamous cell carcinoma
by: M. Tamba, et al.
Published: (2025-06-01)

Three-dimensional conformal radiation for esophageal squamous cell carcinoma with involved-field irradiation may deliver considerable doses of incidental nodal irradiation
by: Ji Kai, et al.
Published: (2012-11-01)

The prognosis value of CONUT and SIS score for recurrent or metastatic esophageal squamous cell carcinoma patients treated with second-line immunotherapy
by: Xiao-Han Zhao, et al.
Published: (2023-06-01)

Extensive clinical target volume in postoperative chemoradiotherapy for esophageal squamous cell carcinoma: a phase II clinical trial (ESO-Shanghai 9)
by: Dashan Ai, et al.
Published: (2023-02-01)

Real-world clinical outcomes of nivolumab and taxane as a second- or later-line therapy for recurrent or unresectable advanced esophageal squamous cell carcinoma
by: Manato Ohsawa, et al.
Published: (2023-04-01)

Safety and tolerability of first‐line durvalumab with tremelimumab and chemotherapy in esophageal squamous cell carcinoma
by: Dae Ho Lee, et al.
Published: (2023-08-01)

Incorporation of PET Metabolic Parameters With Clinical Features Into a Predictive Model for Radiotherapy-Related Esophageal Fistula in Esophageal Squamous Cell Carcinoma
by: Kaixin Li, et al.
Published: (2022-02-01)

Corrigendum: The prognosis value of CONUT and SIS score for recurrent or metastatic esophageal squamous cell carcinoma patients treated with second-line immunotherapy
by: Xiao-Han Zhao, et al.
Published: (2023-12-01)

Perioperative Outcomes of Minimally Invasive Esophagectomy After Neoadjuvant Immunotherapy for Patients With Locally Advanced Esophageal Squamous Cell Carcinoma
by: Jiahan Cheng, et al.
Published: (2022-03-01)

Effect of modern high-dose versus standard-dose radiation in definitive concurrent chemo-radiotherapy on outcome of esophageal squamous cell cancer: a meta-analysis
by: He-San Luo, et al.
Published: (2019-10-01)

New Trend of Surgery in Locally Advanced Esophageal Squamous Cell Carcinoma Patients
by: Tatcha Rerkrak, et al.
Published: (2021-11-01)

Factors affecting survival in esophageal squamous cell carcinoma: Single-center experience
by: Abdullah Sakin, et al.
Published: (2020-05-01)

Short-term response might influence the treatment-related benefit of adjuvant chemotherapy after concurrent chemoradiotherapy for esophageal squamous cell carcinoma patients
by: Ao Liu, et al.
Published: (2021-10-01)

The Correlation between the Expression of Long Non-coding RNA UCA1 andthe Radio-sensitivity of Esophageal Squamous Cell Carcinoma Patients
by: Guangpeng Pan, et al.
Published: (2024-03-01)

Evaluation of pembrolizumab plus cisplatin and fluorouracil in radical treatment for patients with T4b esophageal squamous cell carcinoma
by: Nobukazu Hokamura, et al.
Published: (2024-09-01)

The Impact of Radiotherapy Dose in Patients with Locally Advanced Esophageal Squamous Cell Carcinoma Receiving Preoperative Chemoradiotherapy
by: Chien-Ming Lo, et al.
Published: (2021-03-01)

Advancing precision medicine in esophageal squamous cell carcinoma using patient-derived organoids
by: Suya Shen, et al.
Published: (2024-12-01)