FCGR3A F158V alleles frequency differs in multiple myeloma patients from healthy population

FCGR3A presents a single nucleotide polymorphism at location 158 (V/F), which affects its binding to the fragment crystallizable (Fc) of antibodies (Abs). FcγRIIIa-158 V allotype has the highest affinity and is associated with a better clinical response to IgG1 monoclonal Abs (mAb) treatment. We com...

وصف كامل

التفاصيل البيبلوغرافية
الحاوية / القاعدة:	OncoImmunology
المؤلفون الرئيسيون:	Michaël Constantinides, Nicolas Robert, Caroline Multrier, Loïs Coënon, Mauricio Campos-Mora, Carine Jacquard, Fei Gao, Sara Zemiti, Jessy Presumey, Guillaume Cartron, Jérome Moreaux, Martin Villalba
التنسيق:	مقال
اللغة:	الإنجليزية
منشور في:	Taylor & Francis Group 2024-12-01
الموضوعات:	FCGR3A polymorphism FcγRIIIa/CD16a monoclonal gammopathy of undetermined significance (MGUS) multiple myeloma (MM) tumor environment
الوصول للمادة أونلاين:	https://www.tandfonline.com/doi/10.1080/2162402X.2024.2388306

مواد مشابهة

Combined FCGR2A (131H/R) and FCGR3A (158F/V) genotypes and their gender-specific association with chronic and refractory immune thrombocytopenia in Palestinian children
حسب: Khitam Amer, وآخرون
منشور في: (2025-10-01)

Oral, periorbital, and inguinal purpura in a patient with paraproteinemia
حسب: Donn LaTour, BS, وآخرون
منشور في: (2022-09-01)

Ulcerating necrobiotic xanthogranuloma: A clinical sign to reconsider progression from MGUS to multiple myeloma
حسب: Christopher J. Fay, BA, وآخرون
منشور في: (2023-10-01)

FCGR3A V158F gene polymorphism and trastuzumab response in HER2-positive breast cancer patients
حسب: Marwa A. Abdel-Wahed, وآخرون
منشور في: (2024-10-01)

Single Nucleotide Polymorphism rs10919543 in FCGR2A/FCGR3A Region Confers Susceptibility to Takayasu Arteritis in Chinese Population
حسب: Fang Qin, وآخرون
منشور في: (2016-01-01)

Pulmonary nodules associated with pulmonary embolism: A rare and misleading presentation of amyloidosis
حسب: Trescos Florent, وآخرون
منشور في: (2020-01-01)

A Case of M-Paraprotein-Associated Polyneuropathy with Stable Response to Rituximab Therapy
حسب: VG Potapenko, وآخرون
منشور في: (2019-09-01)

Identifying monoclonal gammopathy of undetermined significance from electronic health records
حسب: Hilary C. Tanenbaum, وآخرون
منشور في: (2023-03-01)

Association of FCGR2A rs1801274 and FCGR3A rs396991 polymorphisms with various autoimmune diseases: a meta-analysis
حسب: Elena Thaler, وآخرون
منشور في: (2025-09-01)

Determination of the target of monoclonal immunoglobulins: a novel diagnostic tool for individualized MGUS therapy, and prevention and therapy of smoldering and multiple myeloma
حسب: Sylvie Hermouet, وآخرون
منشور في: (2023-10-01)

A gene signature can predict risk of MGUS progressing to multiple myeloma
حسب: Fumou Sun, وآخرون
منشور في: (2023-06-01)

An Engineered Human Fc variant With Exquisite Selectivity for FcγRIIIaV158 Reveals That Ligation of FcγRIIIa Mediates Potent Antibody Dependent Cellular Phagocytosis With GM-CSF-Differentiated Macrophages
حسب: Tae Hyun Kang, وآخرون
منشور في: (2019-03-01)

Influence of CD16 (FcγRIII) Expression on Peripheral Blood Mononuclear Cells on Response to Treatment with Rituximab in Pemphigus: A Cross-Sectional Study
حسب: Ankur Sharma, وآخرون
منشور في: (2025-07-01)

Comparative Analysis of <i>FCGR</i> Gene Polymorphism in Pulmonary Sarcoidosis and Tuberculosis
حسب: Marlena Typiak, وآخرون
منشور في: (2023-04-01)

FCGR2/3 polymorphisms are associated with susceptibility to Kawasaki disease but do not predict intravenous immunoglobulin resistance and coronary artery aneurysms
حسب: Paula Uittenbogaard, وآخرون
منشور في: (2024-09-01)

IS IT POSSIBLE TO PREDICT TUMOR PROGRESSION THROUGH GENOMIC CHARACTERIZATION OF MONOCLONAL GAMMOPATHY AND SMOLDERING MULTIPLE MYELOMA?
حسب: Ugo Testa, وآخرون
منشور في: (2024-04-01)

Falsely abnormal serum protein electrophoresis after administration of intravenous immunoglobulins (IVIG): A retrospective cohort study
حسب: Andrew Sulaiman, وآخرون
منشور في: (2024-11-01)

A case of benign immunoglobulin D monoclonal gammopathy of undetermined significance with 26 years of follow‐up
حسب: Larry D. Anderson Jr., وآخرون
منشور في: (2024-02-01)

Hematologic mask of infective endocarditis as a cause of fever of unknown origin: a case report
حسب: Yu. A. Lutokhina, وآخرون
منشور في: (2024-09-01)

Spatial transcriptomics reveals distinct role of monocytes/macrophages with high FCGR3A expression in kidney transplant rejections
حسب: Yan Chen Wongworawat, وآخرون
منشور في: (2025-09-01)

Erythema elevatum diutinum–associated with loss of the uvula
حسب: Jonathan Kentley, MBBS, وآخرون
منشور في: (2017-05-01)

Modeling of clinical phenotypes in systemic lupus erythematosus based on the platelet transcriptome and FCGR2a genotype
حسب: MacIntosh G. Cornwell, وآخرون
منشور في: (2023-04-01)

The Effect of FcγRIIIA Gene Polymorphism on the Treatment of Diffuse Large B-cell Non-Hodgkin Lymphoma: A Multicenter Prospective Observational Study
حسب: Nurhilal Büyükkurt, وآخرون
منشور في: (2015-05-01)

The “Undetermined Significance” of <sup>18</sup>F-FDG PET/CT or PET/MRI in Patients with Monoclonal Gammopathy of Undetermined Significance (MGUS)
حسب: Giorgio Treglia, وآخرون
منشور في: (2021-08-01)

Increased levels of a pro-inflammatory IgG receptor in the midbrain of people with schizophrenia
حسب: A. Petty, وآخرون
منشور في: (2022-07-01)

FCGR2A defines prognostic immune subtypes and drives tumor progression in hepatocellular carcinoma
حسب: Deyuan Zhong, وآخرون
منشور في: (2025-10-01)

FcγRIIIA -activating antibodies in dengue virus infection reveals a distinct transient cross-reactive profile
حسب: Claudio Soto-Garita, وآخرون
منشور في: (2025-09-01)

Fc‐gamma receptor polymorphisms, cetuximab therapy, and overall survival in the CCTG CO.20 trial of metastatic colorectal cancer
حسب: Daniel Shepshelovich, وآخرون
منشور في: (2018-11-01)

Monoclonal gammopathy of renal significance: From bench to bedside
حسب: Megha Saigal, وآخرون
منشور في: (2025-01-01)

Integrated transcriptomics and proteomics assay identifies the role of FCGR1A in maintaining sperm fertilization capacity during semen cryopreservation in sheep
حسب: Jiachen Bai, وآخرون
منشور في: (2023-08-01)

Plant-related quality attributes affecting FcγRIIIa binding: affinity chromatography analysis of rituximab glycovariants from Nicotiana benthamiana
حسب: Sara Tengattini, وآخرون
منشور في: (2025-06-01)

In silico evaluation of the role of Fab glycosylation in cetuximab antibody dynamics
حسب: Simona Saporiti, وآخرون
منشور في: (2024-08-01)

Comparison of Monoclonal Gammopathies Linked to Poliovirus or Coxsackievirus vs. Other Infectious Pathogens
حسب: Jean Harb, وآخرون
منشور في: (2021-02-01)

Impact of FCGR2A rs1801274 and IL-6R rs2228145 polymorphisms on tocilizumab response in the Iranian population with severe COVID-19
حسب: Nastaran Injinari, وآخرون
منشور في: (2024-10-01)

Electrophoretical distribution of serum monoclonal protein and underlying causes. Data from a referral center in Mexico
حسب: Luz Tarín-Arzaga, وآخرون
منشور في: (2022-01-01)

Clinical clues for suspecting wild-type transthyretin cardiac amyloidosis in patients with monoclonal gammopathy of undetermined significance: a case report
حسب: Tomoaki Haga, وآخرون
منشور في: (2024-06-01)

Editorial: Modulation of antibody-mediated effector functions in natural killer cells: protective and detrimental effects in infectious diseases
حسب: Ricciarda Galandrini, وآخرون
منشور في: (2024-04-01)

Integrative Pan-Cancer Analysis Confirmed that FCGR3A is a Candidate Biomarker Associated With Tumor Immunity
حسب: Lilin Li, وآخرون
منشور في: (2022-05-01)

Polyneuropathy Associated with IgM Monoclonal Gammopathy; Advances in Genetics and Treatment, Focusing on Anti-MAG Antibodies
حسب: Johannes P. M. van de Mortel, وآخرون
منشور في: (2022-10-01)

A case of immunotactoid glomerulopathy with false-negative IgG staining
حسب: Shuma Hirashio, وآخرون
منشور في: (2018-06-01)