Switching on lysosomes
The formation of large endolysosomal structures in unfertilized eggs ensures that lysosomes remain dormant before fertilization, and then shift into clean-up mode after the egg-to-embryo transition.
| Published in: | eLife |
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| Main Authors: | , |
| Format: | Article |
| Language: | English |
| Published: |
eLife Sciences Publications Ltd
2024-08-01
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| Subjects: | |
| Online Access: | https://elifesciences.org/articles/102430 |
| _version_ | 1850345121393934336 |
|---|---|
| author | Deepak Adhikari John Carroll |
| author_facet | Deepak Adhikari John Carroll |
| author_sort | Deepak Adhikari |
| collection | DOAJ |
| container_title | eLife |
| description | The formation of large endolysosomal structures in unfertilized eggs ensures that lysosomes remain dormant before fertilization, and then shift into clean-up mode after the egg-to-embryo transition. |
| format | Article |
| id | doaj-art-426475e27e4e4cfdb5adba150e6d40e0 |
| institution | Directory of Open Access Journals |
| issn | 2050-084X |
| language | English |
| publishDate | 2024-08-01 |
| publisher | eLife Sciences Publications Ltd |
| record_format | Article |
| spelling | doaj-art-426475e27e4e4cfdb5adba150e6d40e02025-08-19T23:12:26ZengeLife Sciences Publications LtdeLife2050-084X2024-08-011310.7554/eLife.102430Switching on lysosomesDeepak Adhikari0https://orcid.org/0000-0002-3404-8753John Carroll1https://orcid.org/0000-0001-9644-5861Development and Stem Cell Program and the Department of Anatomy and Developmental Biology, Monash Biomedicine Discovery Institute, Monash University, Melbourne, AustraliaDevelopment and Stem Cell Program and the Department of Anatomy and Developmental Biology, Monash Biomedicine Discovery Institute, Monash University, Melbourne, AustraliaThe formation of large endolysosomal structures in unfertilized eggs ensures that lysosomes remain dormant before fertilization, and then shift into clean-up mode after the egg-to-embryo transition.https://elifesciences.org/articles/102430fertilizationELYSAoocyteembryolysosomeendosome |
| spellingShingle | Deepak Adhikari John Carroll Switching on lysosomes fertilization ELYSA oocyte embryo lysosome endosome |
| title | Switching on lysosomes |
| title_full | Switching on lysosomes |
| title_fullStr | Switching on lysosomes |
| title_full_unstemmed | Switching on lysosomes |
| title_short | Switching on lysosomes |
| title_sort | switching on lysosomes |
| topic | fertilization ELYSA oocyte embryo lysosome endosome |
| url | https://elifesciences.org/articles/102430 |
| work_keys_str_mv | AT deepakadhikari switchingonlysosomes AT johncarroll switchingonlysosomes |