Pixel-wise programmability enables dynamic high-SNR cameras for high-speed microscopy

Abstract High-speed wide-field fluorescence microscopy has the potential to capture biological processes with exceptional spatiotemporal resolution. However, conventional cameras suffer from low signal-to-noise ratio at high frame rates, limiting their ability to detect faint fluorescent events. Her...

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Bibliographic Details
Published in:Nature Communications
Main Authors: Jie Zhang, Jonathan Newman, Zeguan Wang, Yong Qian, Pedro Feliciano-Ramos, Wei Guo, Takato Honda, Zhe Sage Chen, Changyang Linghu, Ralph Etienne-Cummings, Eric Fossum, Edward Boyden, Matthew Wilson
Format: Article
Language:English
Published: Nature Portfolio 2024-05-01
Online Access:https://doi.org/10.1038/s41467-024-48765-5

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