Histone deacetylases facilitate the accurate repair of broken forks

We have recently uncovered that loss of the yeast histone deacetylases Rpd3 (Reduced Potassium Dependency 3) and Hda1 (Histone DeAcetylase 3) affects the cohesion between sister chromatids thus impairing repair of DNA damage at replication forks and enhancing genetic instability. Here we discuss the...

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Bibliographic Details
Published in:	Molecular & Cellular Oncology
Main Authors:	Belén Gómez-González, Pedro Ortega, Andrés Aguilera
Format:	Article
Language:	English
Published:	Taylor & Francis Group 2020-03-01
Subjects:	histone deacetylases histone deacetylase inhibitors double-strand break repair cohesion sister-chromatid recombination
Online Access:	http://dx.doi.org/10.1080/23723556.2019.1705731

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