Bioactivated Glucoraphanin Modulates Genes Involved in Necroptosis on Motor-Neuron-like Nsc-34: A Transcriptomic Study
Research on bioactive compounds has grown recently due to their health benefits and limited adverse effects, particularly in reducing the risk of chronic diseases, including neurodegenerative conditions. According to these observations, this study investigates the activity of sulforaphane (RS-GRA) o...
| Published in: | Antioxidants |
|---|---|
| Main Authors: | Aurelio Minuti, Alessandra Trainito, Agnese Gugliandolo, Ivan Anchesi, Luigi Chiricosta, Renato Iori, Emanuela Mazzon, Marco Calabrò |
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2024-09-01
|
| Subjects: | |
| Online Access: | https://www.mdpi.com/2076-3921/13/9/1111 |
Similar Items
α-Cyclodextrin/Moringin Induces an Antioxidant Transcriptional Response Activating Nrf2 in Differentiated NSC-34 Motor Neurons
by: Agnese Gugliandolo, et al.
Published: (2024-07-01)
by: Agnese Gugliandolo, et al.
Published: (2024-07-01)
Reduction of the sulfoxide in glucoraphanin and sulforaphane by E. coli VL11 and BL21 (DE3)
by: Vijitra Luang-In, et al.
Published: (2016-12-01)
by: Vijitra Luang-In, et al.
Published: (2016-12-01)
Cannabinol Regulates the Expression of Cell Cycle-Associated Genes in Motor Neuron-like NSC-34: A Transcriptomic Analysis
by: Alessandra Trainito, et al.
Published: (2024-06-01)
by: Alessandra Trainito, et al.
Published: (2024-06-01)
Glucosinolate Metabolites and Brain Health: An Updated Review on Their Potential Benefits in Neurodegenerative, Neurodevelopmental, and Psychiatric Disorders
by: Claudia Muscarà, et al.
Published: (2025-07-01)
by: Claudia Muscarà, et al.
Published: (2025-07-01)
Cannabigerol Activates Cytoskeletal Remodeling via Wnt/PCP in NSC-34: An In Vitro Transcriptional Study
by: Ivan Anchesi, et al.
Published: (2023-01-01)
by: Ivan Anchesi, et al.
Published: (2023-01-01)
Cannabinol (CBN) Influences the Ion Channels and Synaptic-Related Genes in NSC-34 Cell Line: A Transcriptomic Study
by: Alessandra Trainito, et al.
Published: (2024-09-01)
by: Alessandra Trainito, et al.
Published: (2024-09-01)
Cannabinerol (CBNR) Influences Synaptic Genes Associated with Cytoskeleton and Ion Channels in NSC-34 Cell Line: A Transcriptomic Study
by: Osvaldo Artimagnella, et al.
Published: (2024-01-01)
by: Osvaldo Artimagnella, et al.
Published: (2024-01-01)
The Transcriptomic Analysis of NSC-34 Motor Neuron-Like Cells Reveals That Cannabigerol Influences Synaptic Pathways: A Comparative Study with Cannabidiol
by: Agnese Gugliandolo, et al.
Published: (2020-10-01)
by: Agnese Gugliandolo, et al.
Published: (2020-10-01)
Induction of Apoptosis by Gluconasturtiin-Isothiocyanate (GNST-ITC) in Human Hepatocarcinoma HepG2 Cells and Human Breast Adenocarcinoma MCF-7 Cells
by: Asvinidevi Arumugam, et al.
Published: (2020-03-01)
by: Asvinidevi Arumugam, et al.
Published: (2020-03-01)
Transcriptomic Profiling after In Vitro Δ<sup>8</sup>-THC Exposure Shows Cytoskeletal Remodeling in Trauma-Injured NSC-34 Cell Line
by: Luigi Chiricosta, et al.
Published: (2023-09-01)
by: Luigi Chiricosta, et al.
Published: (2023-09-01)
Will Cannabigerol Trigger Neuroregeneration after a Spinal Cord Injury? An In Vitro Answer from NSC-34 Scratch-Injured Cells Transcriptome
by: Andrea Valeri, et al.
Published: (2022-01-01)
by: Andrea Valeri, et al.
Published: (2022-01-01)
Cannabichromene Induces Neuronal Differentiation in NSC-34 Cells: Insights from Transcriptomic Analysis
by: Andrea Valeri, et al.
Published: (2023-03-01)
by: Andrea Valeri, et al.
Published: (2023-03-01)
Beneficial Health Effects of Glucosinolates-Derived Isothiocyanates on Cardiovascular and Neurodegenerative Diseases
by: Ramla Muhammad Kamal, et al.
Published: (2022-01-01)
by: Ramla Muhammad Kamal, et al.
Published: (2022-01-01)
Bioavailability, Human Metabolism, and Dietary Interventions of Glucosinolates and Isothiocyanates: Critical Insights and Future Perspectives
by: Federica Narra, et al.
Published: (2025-08-01)
by: Federica Narra, et al.
Published: (2025-08-01)
The Impact of Sulforaphane on Sex-Specific Conditions and Hormone Balance: A Comprehensive Review
by: Jed W. Fahey, et al.
Published: (2025-01-01)
by: Jed W. Fahey, et al.
Published: (2025-01-01)
Diversity of glucosinolates among common Brassicaceae vegetables in China
by: Biao Zhu, et al.
Published: (2023-06-01)
by: Biao Zhu, et al.
Published: (2023-06-01)
‘Kombucha’-like Beverage of Broccoli By-Products: A New Dietary Source of Bioactive Sulforaphane
by: Berta María Cánovas, et al.
Published: (2023-10-01)
by: Berta María Cánovas, et al.
Published: (2023-10-01)
Assessment of Methodological Pipelines for the Determination of Isothiocyanates Derived from Natural Sources
by: Sotiris Kyriakou, et al.
Published: (2022-03-01)
by: Sotiris Kyriakou, et al.
Published: (2022-03-01)
Bioavailability Study of Isothiocyanates and Other Bioactive Compounds of <i>Brassica oleracea</i> L. var. Italica Boiled or Steamed: Functional Food or Dietary Supplement?
by: Patrick Orlando, et al.
Published: (2022-01-01)
by: Patrick Orlando, et al.
Published: (2022-01-01)
Isothiocyanates, Nitriles, and Epithionitriles from Glucosinolates Are Affected by Genotype and Developmental Stage in Brassica oleracea Varieties
by: Franziska S. Hanschen, et al.
Published: (2017-06-01)
by: Franziska S. Hanschen, et al.
Published: (2017-06-01)
Stability studies of isothiocyanates and nitriles in aqueous media
by: Vijitra Luang-In, et al.
Published: (2015-12-01)
by: Vijitra Luang-In, et al.
Published: (2015-12-01)
Editorial: Glucosinolate Metabolites: Bioavailability, Bioactivity and Clinical Variability
by: Donato Angelino, et al.
Published: (2021-12-01)
by: Donato Angelino, et al.
Published: (2021-12-01)
Bioavailability of glucosinolates and their breakdown products: Impact of processing
by: Francisco Jose Barba, et al.
Published: (2016-08-01)
by: Francisco Jose Barba, et al.
Published: (2016-08-01)
Photoprotective Properties of Isothiocyanate and Nitrile Glucosinolate Derivatives From Meadowfoam (Limnanthes alba) Against UVB Irradiation in Human Skin Equivalent
by: Evan L. Carpenter, et al.
Published: (2018-05-01)
by: Evan L. Carpenter, et al.
Published: (2018-05-01)
Cannabinerol Prevents Endoplasmic Reticulum and Mitochondria Dysfunctions in an In Vitro Model of Alzheimer’s Disease: A Network-Based Transcriptomic Analysis
by: Luigi Chiricosta, et al.
Published: (2024-06-01)
by: Luigi Chiricosta, et al.
Published: (2024-06-01)
Glucosinolates as undesirable substances in animal feed ‐ Scientific Opinion of the Panel on Contaminants in the Food Chain
by: European Food Safety Authority (EFSA)
Published: (2008-01-01)
by: European Food Safety Authority (EFSA)
Published: (2008-01-01)
Glucosinolates, a natural chemical arsenal: More to tell than the myrosinase story
by: Roula M. Abdel-Massih, et al.
Published: (2023-04-01)
by: Roula M. Abdel-Massih, et al.
Published: (2023-04-01)
Seed germination and sprouts production of Moringa oleifera: A potential functional food?
by: José A. Núñez-Gastélum, et al.
Published: (2023-05-01)
by: José A. Núñez-Gastélum, et al.
Published: (2023-05-01)
The Influence of Different Hydrothermal Processes Used in the Preparation of Brussels Sprouts on the Availability of Glucosinolates to Humans
by: Anna Sadowska-Rociek, et al.
Published: (2024-09-01)
by: Anna Sadowska-Rociek, et al.
Published: (2024-09-01)
Turning glucosinolate into allelopathic fate: investigating allyl isothiocyanate variability and nitrile formation in eco-friendly Brassica juncea from South Korea
by: Da-Yeong Ko, et al.
Published: (2024-07-01)
by: Da-Yeong Ko, et al.
Published: (2024-07-01)
Natural Compounds and Glutathione: Beyond Mere Antioxidants
by: Claudia Di Giacomo, et al.
Published: (2023-07-01)
by: Claudia Di Giacomo, et al.
Published: (2023-07-01)
Chemical composition of moringa oleifera and cruciferous plants and their anti-inflammatory properties
by: Wolff Khea, et al.
Published: (2023-01-01)
by: Wolff Khea, et al.
Published: (2023-01-01)
Factors Influencing Glucoraphanin and Sulforaphane Formation in Brassica Plants: A Review
by: Zhen-xin GU, et al.
Published: (2012-11-01)
by: Zhen-xin GU, et al.
Published: (2012-11-01)
Cloning and function verification of epithiospecifier protein gene from Chinese cabbage
by: SUN Hai-yan, et al.
Published: (2012-09-01)
by: SUN Hai-yan, et al.
Published: (2012-09-01)
An Integrated Metabolomics Study of Glucosinolate Metabolism in Different Brassicaceae Genera
by: Yu Liu, et al.
Published: (2020-07-01)
by: Yu Liu, et al.
Published: (2020-07-01)
Biofumigation – use of specialized cover crops in plant protection
by: Dinka Grubišić, et al.
Published: (2022-07-01)
by: Dinka Grubišić, et al.
Published: (2022-07-01)
Dietary glucosinolates derived isothiocyanates: chemical properties, metabolism and their potential in prevention of Alzheimer’s disease
by: Farhana Khan, et al.
Published: (2023-07-01)
by: Farhana Khan, et al.
Published: (2023-07-01)
Seasonal Variation of Glucosinolate Hydrolysis Products in Commercial White and Red Cabbages (<i>Brassica oleracea</i> var. <i>capitata</i>)
by: Nicole S. Wermter, et al.
Published: (2020-11-01)
by: Nicole S. Wermter, et al.
Published: (2020-11-01)
Anticancer Activity, Mechanism, and Delivery of Allyl Isothiocyanate
by: Ammar Tarar, et al.
Published: (2022-09-01)
by: Ammar Tarar, et al.
Published: (2022-09-01)
Inactivation of Thioglucosidase from <i>Sinapis alba</i> (White Mustard) Seed by Metal Salts
by: Monika Marcinkowska, et al.
Published: (2020-09-01)
by: Monika Marcinkowska, et al.
Published: (2020-09-01)
Similar Items
-
α-Cyclodextrin/Moringin Induces an Antioxidant Transcriptional Response Activating Nrf2 in Differentiated NSC-34 Motor Neurons
by: Agnese Gugliandolo, et al.
Published: (2024-07-01) -
Reduction of the sulfoxide in glucoraphanin and sulforaphane by E. coli VL11 and BL21 (DE3)
by: Vijitra Luang-In, et al.
Published: (2016-12-01) -
Cannabinol Regulates the Expression of Cell Cycle-Associated Genes in Motor Neuron-like NSC-34: A Transcriptomic Analysis
by: Alessandra Trainito, et al.
Published: (2024-06-01) -
Glucosinolate Metabolites and Brain Health: An Updated Review on Their Potential Benefits in Neurodegenerative, Neurodevelopmental, and Psychiatric Disorders
by: Claudia Muscarà, et al.
Published: (2025-07-01) -
Cannabigerol Activates Cytoskeletal Remodeling via Wnt/PCP in NSC-34: An In Vitro Transcriptional Study
by: Ivan Anchesi, et al.
Published: (2023-01-01)
