CD19-immunoPET for noninvasive visualization of CD19 expression in B-cell lymphoma patients

Abstract Cell- and antibody-based CD19-directed therapies have demonstrated great potential for treating B-cell non-Hodgkin lymphoma (B-NHL). However, all these approaches suffer from limited response rates and considerable toxicity. Until now, therapy decisions have been routinely based on histopat...

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Bibliographic Details

Published in:	Biomarker Research
Main Authors:	Dominik Sonanini, Johannes Schwenck, Simone Blaess, Julia Schmitt, Andreas Maurer, Walter Ehrlichmann, Malte Ritter, Julia Skokowa, Manfred Kneilling, Gundram Jung, Falko Fend, Simon Krost, Christian M. Seitz, Peter Lang, Gerald Reischl, Rupert Handgretinger, Christian la Fougère, Bernd J. Pichler
Format:	Article
Language:	English
Published:	BMC 2024-05-01
Subjects:	CD19 Positron emission tomography Imaging biomarker Theranostics CAR-T cells Molecular imaging
Online Access:	https://doi.org/10.1186/s40364-024-00595-9