Budesonide Enemas for Topical Therapy of Ulcerative Colitis

Budesonide is a nonhalogenated glucocorticosteroid that is very suitable for topical therapy in left-sided colitis because it has a high ratio of topical to systemic activity. Although it is absorbed, it is very rapidly metabolized by the liver (first pass metabolism). It does not suppress the hypot...

Full description

Bibliographic Details
Published in:	Canadian Journal of Gastroenterology
Main Author:	P Rutgeerts
Format:	Article
Language:	English
Published:	Wiley 1990-01-01
Online Access:	http://dx.doi.org/10.1155/1990/583849

Similar Items

Topical Treatment of Ulcerative Colitis using Enemas Containing 5-Aminosalicylic Acid and Beclomethasone Dipropionate
by: M Campieri, et al.
Published: (1990-01-01)

Early resolution of bowel urgency by budesonide foam enema results in improved quality of life in patients with ulcerative colitis: a multicenter prospective observational study
by: Taku Kobayashi, et al.
Published: (2025-04-01)

Exacerbation of Ulcerative Colitis following Administration of 5-ASA Enemas
by: Barbara A. Young, et al.
Published: (1989-01-01)

Efficacy of 5-Aminosalicylic Acid Enemas in the Treatment of Distal Ulcerative Colitis
by: MG Robinson, et al.
Published: (1990-01-01)

Budesonide ММХ in the treatment of ulcerative colitis: real world clinical practice
by: P. A. Makarchuk, et al.
Published: (2019-12-01)

5-Aminosalicylic Acid Enemas in the Maintenance of Remission in Distal Ulcerative Colitis and Proctitis
by: Lloyd R Sutherland, et al.
Published: (1987-01-01)

Preparation and characterization of pH-sensitive nanoparticles of budesonide for the treatment of ulcerative colitis
by: Zhou H, et al.
Published: (2018-08-01)

Risk Factors for Relapse and Recurrence of Ulcerative Colitis and Crohn’s Disease
by: Paul Rutgeerts
Published: (1993-01-01)

A systematic review of the efficacy of traditional Chinese medicine retention enema in the treatment of ulcerative colitis
by: Jiaji Li, et al.
Published: (2024-01-01)

Mucoadhesive Nanoparticles Enhance the Therapeutic Effect of Dexamethasone on Experimental Ulcerative Colitis by the Local Administration as an Enema
by: Dong K, et al.
Published: (2023-01-01)

Efficiency of a novel thermosensitive enema in situ hydrogel carrying Periplaneta americana extracts for the treatment of ulcerative colitis
by: Ming Wu, et al.
Published: (2023-02-01)

Kuiyangling Enema Alleviates Ulcerative Colitis Mice by Reducing Levels of Intestinal NETs and Promoting HuR/VDR Signaling
by: Zhang D, et al.
Published: (2025-01-01)

Clinical observation of probiotics combined with mesalazine and Yiyi Baitouweng Decoction retention enema in treating mild-to-moderate ulcerative colitis
by: Li Yanlong, et al.
Published: (2025-02-01)

Nicotine Enemas for Active Crohn's Colitis: An Open Pilot Study
by: J. R. Ingram, et al.
Published: (2008-01-01)

PVA enema ameliorates DSS-induced acute colitis in mice
by: Zhiyong Zhang, et al.
Published: (2023-10-01)

Locally Acting Budesonide-Loaded Solid Self-Microemulsifying Drug Delivery Systems (SMEDDS) for Distal Ulcerative Colitis
by: Ali HSM, et al.
Published: (2024-11-01)

Middle-term prognosis in patients with ulcerative colitis who achieved clinical and endoscopic remission by budesonide rectal foam.
by: Makoto Naganuma, et al.
Published: (2019-01-01)

Budesonide MMX versus prednisolone in mesalamine-refractory mild to moderate ulcerative colitis: a randomized controlled clinical trial
by: Ashraf M. Osman, et al.
Published: (2025-09-01)

Surface-anchored microbial enzyme-responsive solid lipid nanoparticles enabling colonic budesonide release for ulcerative colitis treatment
by: Yipeng Zhang, et al.
Published: (2023-05-01)

Bowel frequency (night) and urgent defecation are improved by budesonide foam in patients with ulcerative colitis: a retrospective observational study
by: Ryosuke Miyazaki, et al.
Published: (2022-06-01)

Integrated Network Pharmacology, Molecular Docking and Animal Experiment to Explore the Efficacy and Potential Mechanism of Baiyu Decoction Against Ulcerative Colitis by Enema
by: Cui Y, et al.
Published: (2023-11-01)

Effects of Yunnan Baiyao retention enema combined with mesalazine enteric-coated tablets and bifidobacterium triple viable capsules for treating ulcerative colitis
by: Liu Junjie, et al.
Published: (2022-04-01)

Expression of Concern: Middle-term prognosis in patients with ulcerative colitis who achieved clinical and endoscopic remission by budesonide rectal foam.
by: PLOS ONE Editors
Published: (2023-01-01)

Expression of Concern: Middle-term prognosis in patients with ulcerative colitis who achieved clinical and endoscopic remission by budesonide rectal foam
Published: (2023-01-01)

Prevention of Relapse in Ulcerative Colitis Using Oral or Topical 5-Aminosalicylic Acid Therapy
by: Lloyd R Sutherland
Published: (1993-01-01)

Esophageal Crohn's Disease Treated “Topically” with Swallowed Aerosolized Budesonide
by: Petros Zezos, et al.
Published: (2010-01-01)

LianChuang ZhiXue Liquid Enema Modulates the Macrophage Polarization of Ulcerative Colitis via Inhibiting the Jagged-1/Notch1 Signaling Pathway
by: Zhang Y, et al.
Published: (2025-04-01)

The Effect of Budesonide that is the Topical Corticosteroid on the Rat Nasal Mucosa (Experimental Study)
by: Atila Güngör, et al.
Published: (2002-03-01)

Oral liposomal delivery of an activatable budesonide prodrug reduces colitis in experimental mice
by: Shiyun Xian, et al.
Published: (2023-12-01)

Assessment of the effectiveness of Budesonide MMX® for active, mild-to-moderate ulcerative colitis in the Polish sub-group of the CORE Practice prospective multi-centre observational study
by: Maciej Jesionowski, et al.
Published: (2023-07-01)

Injection Sclerotherapy for Peptic Ulcer Bleeding
by: Paul Rutgeerts
Published: (1992-01-01)

The use of oral topically acting glucocorticosteroids in the treatment of inflammatory bowel disease
by: P. Rutgeerts
Published: (1998-01-01)

Oral 5-Aminosalicylate, Mesalamine Suppository, and Mesalamine Enema as Initial Therapy for Ulcerative Proctitis in Clinical Practice with Quality of Care Implications
by: James M. Richter, et al.
Published: (2016-01-01)

MESALAZINE PLACE IN THERAPY OF ULCERATIVE COLITIS
by: I. G. Bakulin, et al.
Published: (2017-11-01)

Herbal enema: At the cost of colon
by: Parmanand Prasad, et al.
Published: (2012-01-01)

Comparison of Budesonide Turbuhaler with Budesonide Aqua in the Treatment of Seasonal Allergic Rhinitis
by: William H Yang, et al.
Published: (1998-01-01)

Ulcerative colitis: molecular insights and intervention therapy
by: Yuqing Liang, et al.
Published: (2024-10-01)

Effective domestic mesalazine in the therapy of ulcerative colitis
by: I. N. Ruchkina, et al.
Published: (2021-06-01)

Real-world-data on efficacy and safety of topical budesonide therapy (orodispersible tablet) in induction and maintenance therapy in adult patients with active eosinophilic esophagitis
by: Maja Weisfeld, et al.
Published: (2025-10-01)

The association between drugs and repeated treatment with budesonide in patients with microscopic colitis: a retrospective observational study
by: Oliver Bjurström, et al.
Published: (2024-03-01)