Clinical prognostic factors determining the survival of patients with the Ebola virus

• 出版年: Revista Cubana de Medicina Militar
• 主要な著者: Osvaldo Miranda Gómez, Carlos Manuel Castro Baras, Yoel Alberto Fleites Alonso, José Eduardo Díaz Gómez, Yanetsi Contreras Olive, Sara Anneris Urgellés Carrera
• フォーマット: 論文
• 言語: スペイン語
• 出版事項: Editorial Ciencias Médicas - ECIMED 2020-10-01
• 主題: ebolavirus; fiebre hemorrágica ébola; letalidad; enfermedad por el virus de ébola.
• オンライン･アクセス: http://www.revmedmilitar.sld.cu/index.php/mil/article/view/615
• ISSN: 1561-3046; 1561-3046

Introduction: Ebola virus disease has a high lethality, which is why it is of great interest to carry out research that addresses clinical manifestations that could be prognostic factors for survival. Objective: To evaluate prognostic factors of Ebola patients. Methods: the universe was constituted by the totality (n = 350) of admitted patients. Summary measures were used for qualitative variables, point and interval estimates for quantitative variables, as well as Kaplan-Meier significance tests, Cox regression and Odds Ratio. We worked with a 95% level of reliability. Results: The overall survival was 42.5%. The average survival, approximately 10 days (CI: 9-11 days). Patients who were admitted in serious condition (OR = 3.76), who had low back pain (OR = 2.24), who reported headache (OR = 2.22), who presented fever (OR = 2.16), who they suffered from abdominal pain (OR = 1.95) and who were found to have conjunctival injection (OR = 1.86), were more likely to die than those who entered without these symptoms and signs. Conclusions: Survival was high, despite the complications presented. The symptoms and predictive signs of death in the patients were: the severity of the patient at admission, the presence of low back pain, headache, fever, abdominal pain and conjunctival injection.