Recruitment and remodeling of peridroplet mitochondria in human adipose tissue

Beige adipocyte mitochondria contribute to thermogenesis by uncoupling and by ATP-consuming futile cycles. Since uncoupling may inhibit ATP synthesis, it is expected that expenditure through ATP synthesis is segregated to a disparate population of mitochondria. Recent studies in mouse brown adipocyt...

Full description

Bibliographic Details
Published in:	Redox Biology
Main Authors:	Rebeca Acín-Perez, Anton Petcherski, Michaela Veliova, Ilan Y. Benador, Essam A. Assali, Georgia Colleluori, Saverio Cinti, Alexandra J. Brownstein, Siyouneh Baghdasarian, Masha J. Livhits, Michael W. Yeh, Karthickeyan Chella Krishnan, Laurent Vergnes, Nathan C. Winn, Jaume Padilla, Marc Liesa, Harold S. Sacks, Orian S. Shirihai
Format:	Article
Language:	English
Published:	Elsevier 2021-10-01
Subjects:	Adipose tissue Pheochromocytoma Peridroplet mitochondria Bioenergetics Endocrinology
Online Access:	http://www.sciencedirect.com/science/article/pii/S2213231721002469

Similar Items

Isolation and functional analysis of peridroplet mitochondria from murine brown adipose tissue
by: Jennifer Ngo, et al.
Published: (2021-03-01)

Utilization of Human Samples for Assessment of Mitochondrial Bioenergetics: Gold Standards, Limitations, and Future Perspectives
by: Rebeca Acin-Perez, et al.
Published: (2021-09-01)

Molecular mechanisms of lipid droplets-mitochondria coupling in obesity and metabolic syndrome: insights and pharmacological implications
by: Chunmei Zhang, et al.
Published: (2024-11-01)

Lipid droplet - mitochondria coupling: A novel lipid metabolism regulatory hub in diabetic nephropathy
by: Ming Yang, et al.
Published: (2022-10-01)

Assessment of Brown Adipocyte Thermogenic Function by High-throughput Respirometry
by: Kiana Mahdaviani, et al.
Published: (2015-11-01)

Pheochromocytoma: A single-center 20-year experience
by: Lung-Feng Cheng, et al.
Published: (2019-01-01)

Characteristics of different lipid droplet-mitochondrial contacts patterns during lipid droplet metabolism in T2DM-induced MASLD
by: Ye Xu, et al.
Published: (2025-01-01)

NCLX prevents cell death during adrenergic activation of the brown adipose tissue
by: Essam A. Assali, et al.
Published: (2020-07-01)

Peridroplet mitochondria are associated with the severity of MASLD and the prevention of MASLD by diethyldithiocarbamate
by: Xiangyun Sun, et al.
Published: (2024-08-01)

Cystic pheochromocytoma with hypertensive crisis and classic triad diagnosed using point-of-care ultrasound in the emergency department
by: Kun-Yu Lee
Published: (2023-01-01)

Restoration of lysosomal acidification rescues autophagy and metabolic dysfunction in non-alcoholic fatty liver disease
by: Jialiu Zeng, et al.
Published: (2023-05-01)

Diffuse pulmonary hemorrhage as a rare presentation of pheochromocytoma: a case report with review of the literature
by: Abid Rasool, et al.
Published: (2024-08-01)

Right adrenal giant cystic pheochromocytoma: A case report
by: Ichiro Tsuboi, et al.
Published: (2023-05-01)

Pheochromocytomas/Paragangliomas and two cases
by: W. van Vuuren, et al.
Published: (2007-06-01)

CASE OF PHEOCHROMOCYTOMA WITH PERMANENT HYPERTENSION
by: E. V. Yakovleva, et al.
Published: (2019-07-01)

Bilateral Pheochromocytoma with Germline MAX Variant without Family History
by: Shinnosuke Hata, et al.
Published: (2022-05-01)

Pheochromocytoma-induced diffuse alveolar hemorrhage after cholecystectomy: A case report and literature review
by: Xinlian He, et al.
Published: (2024-07-01)

Platelet biomechanics, platelet bioenergetics, and applications to clinical practice and translational research
by: Mitchell J. George, et al.
Published: (2018-07-01)

<b> Determination of lactic and alactic metabolisms of the anaerobic capacity using oxygen uptake</b>
by: Rodrigo Poles Urso, et al.
Published: (2013-07-01)

Case Report: Surgical Intervention Under Pheochromocytoma Multisystem Crisis: Timing and Approach
by: Shengjun Luo, et al.
Published: (2022-06-01)

The Use of Metyrosine in the Treatment of Pheochromocytoma and Paraganglioma Patients: A Review of the Literature
by: Mansura Babayeva, et al.
Published: (2025-05-01)

Pheochromocytoma in pregnancy – a rare but dangerous diagnosis
by: Romana Marušić, et al.
Published: (2022-08-01)

Prolonged hypoglycemia after the resection of pheochromocytoma in a hemodialysis patient
by: Yuya Maezawa, et al.
Published: (2024-11-01)

Malignant pheochromocytoma invading the ureteral wall muscle layer: A case report
by: Guang-Jie Li, et al.
Published: (2024-11-01)

Outcomes following laparoscopic adrenalectomy: Experience of more than two decades at a tertiary care centre
by: Virinder Kumar Bansal, et al.
Published: (2025-01-01)

CT Features of Adrenal Pheochromocytoma: Evaluation with Clinical and Pathological Correlation
by: Sitthipong Srisajjakul, et al.
Published: (2020-07-01)

A comparative analysis of surgically excised hereditary and sporadic pheochromocytomas: Insights from a single‐center experience
by: Narin Nasiroglu Imga, et al.
Published: (2024-06-01)

Recurrent Pheochromocytoma in an Elderly Patient
by: Ammu Thampi Susheela, et al.
Published: (2020-06-01)

The Pheochromocytoma/Paraganglioma syndrome: an overview on mechanisms, diagnosis and management
by: José Viana Lima Junior, et al.
Published: (2023-06-01)

Adrenal Incidentaloma With the Diagnosis of Normotensive Pheochromocytoma: A Case Report
by: Ali AtashAbParvar, et al.
Published: (2023-04-01)

Cushing′s syndrome in a patient with ACTH secreting pheochromocytoma
by: Dharm Raj Singh, et al.
Published: (2000-01-01)

A cardiogenic shock in PICU turned out to be a bilateral pheochromocytoma: A case report
by: Jay Shah, et al.
Published: (2021-01-01)

Metabolic adaptations to acute glucose uptake inhibition converge upon mitochondrial respiration for leukemia cell survival
by: Monika Komza, et al.
Published: (2025-01-01)

Pheochromocytoma metastasis to the central nervous system: a case report and systematic review
by: Justyna Małgorzata Fercho, et al.
Published: (2025-08-01)

Correction: Pheochromocytoma metastasis to the central nervous system: a case report and systematic review
by: Justyna Małgorzata Fercho, et al.
Published: (2025-09-01)

Catecholamine-induced cardiomyopathy and multiple organ failure in pheochromocytoma
by: Joel Thekekara, et al.
Published: (2020-09-01)

Mitochondrial respiratory function in human platelets: Influence of sample preparation, assay buffer, and instrumental platform
by: Craig Porter, et al.
Published: (2025-10-01)

Immune Cell Metabolic Fitness for Life
by: Kevin S. Bittman
Published: (2022-04-01)

Exposure to Sub-Lethal Doses of Permethrin Is Associated with Neurotoxicity: Changes in Bioenergetics, Redox Markers, Neuroinflammation and Morphology
by: Teresita Guadalupe López-Aceves, et al.
Published: (2021-12-01)

Platelet glycogenolysis is important for energy production and function
by: Kanakanagavalli Shravani Prakhya, et al.
Published: (2023-12-01)