New insights into pathogen-mediated modulation of host RNA splicing

Abstract Alternative splicing (AS) regulation of pre-mRNA has been proven to be one of the fundamental layers of plant immune system. How pathogens disrupt plant AS process to suppress plant immunity by secreted effectors remain poorly understood. In the recent study, Gui et al. revealed that a prev...

وصف كامل

التفاصيل البيبلوغرافية
الحاوية / القاعدة:Stress Biology
المؤلفون الرئيسيون: Chuyun Gao, Suomeng Dong
التنسيق: مقال
اللغة:الإنجليزية
منشور في: Springer 2022-08-01
الموضوعات:
الوصول للمادة أونلاين:https://doi.org/10.1007/s44154-022-00053-2
الوصف
الملخص:Abstract Alternative splicing (AS) regulation of pre-mRNA has been proven to be one of the fundamental layers of plant immune system. How pathogens disrupt plant AS process to suppress plant immunity by secreted effectors remain poorly understood. In the recent study, Gui et al. revealed that a previously identified effector PSR1 of Phytophthora interferes with host RNA splicing machinery to modulate small RNA biogenesis, leading to compromised plant immunity. The study provided a novel insight into the importance of AS process during pathogen-host interactions.
تدمد:2731-0450