Geographic distribution of HBsAg subtypes in Brazil Distribuição geográfica dos subtipos de antígenos de HBsAg no Brasil

HBsAg positive serum samples (896) from five brazilian regions were analysed for HBsAg subtypes. The presence of five different subtypes (ayw2, ayw3, ayw4, adw2 and adw4) was detected. In Northern region subtypes adw4 (41.2%) and adw2 (37.2%) were predominant. In the North East only subtype adw2 was...

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Bibliographic Details
Published in:Memorias do Instituto Oswaldo Cruz
Main Authors: Ana Maria Coimbra Gaspar, Clara Fumiko Tachibana Yoshida
Format: Article
Language:English
Published: Fundação Oswaldo Cruz (FIOCRUZ) 1987-06-01
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Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761987000200013
Description
Summary:HBsAg positive serum samples (896) from five brazilian regions were analysed for HBsAg subtypes. The presence of five different subtypes (ayw2, ayw3, ayw4, adw2 and adw4) was detected. In Northern region subtypes adw4 (41.2%) and adw2 (37.2%) were predominant. In the North East only subtype adw2 was encountered. In Central West, South-East and South, subtypes ayw2, ayw3, adw2 and adw4 were present, with predominance of adw2 in Central West and South East (84.3% and 69.4% respectively) whereas in the South the predominant subtype was ayw3 (41.9%) followed by ayw2 (36.4%). Subtypes ayw1, ayr and adr were not found among the samples studied. These results show the difference in the incidence of HBsAg subtypes in the different regions of Brazil and their significance in relation to the colonization and migrations in this country.<br>Foram analisadas 896 amostras de soros HBsAg positivos de cinco regiões brasileiras. A presença de cinco diferentes subtipos (ayw2, ayw3, ayw4, adw2 e adw4) foi determinada. Na região Norte, os subtipos adw4 (41,2%) e adw2 (37,2%) foram predominantes. No Nordeste somente o subtipo adw2 foi encontrado. No centro Oeste, Sudeste e Sul os subtipos ayw2, ayw3, adw4 estão presentes, com predominância do adw2 no Centro Oeste e Sudeste (84,3% e 69,4% respectivamente), enquanto que no Sul o subtipo predominante foi ayw3 (41,9%) seguido pelo ayw2 (36,4%). Os subtipos ayw1 e ayr e adr não foram encontrados entre amostras estudadas. Estes resultados mostram a diferença na incidência dos subtipos do HBsAg em diferentes regiões do Brasil e seu significado em relação à colonização e migrações neste país.
ISSN:0074-0276
1678-8060