An Unusual Presentation of Myasthenia Gravis: Case Report
Abstract Myasthenia gravis is a relatively rare autoimmune disorder of the neuromuscular system. Classically, there is weakness in the voluntary muscles which increases with repetitive activity. Common symptoms include but are not limited to ptosis, diplopia, proximal myopathy, and limb weakness. He...
| Published in: | Egyptian Journal of Critical Care Medicine |
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| Main Authors: | , , , , |
| Format: | Article |
| Language: | English |
| Published: |
Springer
2023-07-01
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| Subjects: | |
| Online Access: | https://doi.org/10.1097/EJ9.0000000000000057 |
| Summary: | Abstract Myasthenia gravis is a relatively rare autoimmune disorder of the neuromuscular system. Classically, there is weakness in the voluntary muscles which increases with repetitive activity. Common symptoms include but are not limited to ptosis, diplopia, proximal myopathy, and limb weakness. Here, we discuss the diagnostic dilemma in the management of a 24-year-old woman who presented in emergency in unconscious state and required mechanical ventilation for respiratory acidosis. There was alleged a history of abnormal respiration during sleep and neck weakness while awake. Clinical examination revealed features of limb spasticity with proximal limb weakness. All the routine investigations and radiological imaging were normal. Subsequent workup revealed elevated anti–muscle–specific kinase antibody and N-acetyl-cysteine–activated creatinine kinase. The present case report highlights the need for high index of suspicion to diagnose such atypical cases. |
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| ISSN: | 2090-7303 2090-9209 |