The Potential of Amphiphilic Cyclodextrins as Carriers for Therapeutic Purposes: A Short Overview

Cyclodextrins, since their discovery in the late 19th century, have gained tremendous interest in biomedical research, beginning with their recognition as safe pharmaceutical excipients, and continuing with exploiting their potential for enhancing the therapeutic response of active pharmaceutical in...

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Bibliographic Details
Published in:Pharmaceutics
Main Authors: Ramona Daniela Pârvănescu, Marius Păpurică, Ionica Oana Alexa, Cristina Adriana Dehelean, Codruța Șoica, Elena Alina Moacă, Adriana Ledeți, Mirela Voicu, Dorina Coricovac, Cristina Trandafirescu
Format: Article
Language:English
Published: MDPI AG 2025-08-01
Subjects:
amphiphilic cyclodextrins
inclusion complexes
solubilising agents
cancer treatment
gene delivery
Online Access:https://www.mdpi.com/1999-4923/17/8/1086
Description
Summary:Cyclodextrins, since their discovery in the late 19th century, have gained tremendous interest in biomedical research, beginning with their recognition as safe pharmaceutical excipients, and continuing with exploiting their potential for enhancing the therapeutic response of active pharmaceutical ingredients, and also to be used as drugs for specific medical purposes. This review presents an integrative perspective on amphiphilic cyclodextrins, the manuscript being divided into two parts, one devoted to the properties of amphiphilic cyclodextrins, while the second one is dedicated to their biomedical applications, with an emphasis on cancer therapy.
ISSN:1999-4923

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