A versatile new tool derived from a bacterial deubiquitylase to detect and purify ubiquitylated substrates and their interacting proteins.

Protein ubiquitylation is an important posttranslational modification affecting a wide range of cellular processes. Due to the low abundance of ubiquitylated species in biological samples, considerable effort has been spent on methods to purify and detect ubiquitylated proteins. We have developed an...

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Bibliographic Details
Published in:	PLoS Biology
Main Authors:	Mengwen Zhang, Jason M Berk, Adrian B Mehrtash, Jean Kanyo, Mark Hochstrasser
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2022-06-01
Online Access:	https://doi.org/10.1371/journal.pbio.3001501

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