Identification of costimulatory molecule signatures for evaluating prognostic risk in non-small cell lung cancer

Background: Non-small cell lung cancer (NSCLC) is a leading cause of cancer-related mortality worldwide. Despite advances in treatment, prognosis remains poor, necessitating the identification of reliable prognostic biomarkers. Costimulatory molecules (CMs) have shown to enhance antitumor immune res...

Full description

Bibliographic Details
Published in:	Heliyon
Main Authors:	Yan Yang, Suqiong Lu, Guomin Gu
Format:	Article
Language:	English
Published:	Elsevier 2024-09-01
Subjects:	Non-small cell lung cancer Costimulatory molecule Prognosis Immunotherapy
Online Access:	http://www.sciencedirect.com/science/article/pii/S2405844024128472

Similar Items

The role of costimulatory molecules in glioma biology and immune microenvironment
by: Ji Wang, et al.
Published: (2022-11-01)

Costimulatory molecule‐related lncRNA model as a potential prognostic biomarker in non‐small cell lung cancer
by: Yuanshan Yao, et al.
Published: (2023-03-01)

Identification of a costimulatory molecule-based signature to predict prognostic risk of pancreatic adenocarcinoma
by: Chao Wu, et al.
Published: (2022-12-01)

LINC00941 Promotes Cell Malignant Behavior and Is One of Five Costimulatory Molecule-Related lncRNAs That Predict Prognosis in Renal Clear Cell Carcinoma
by: Huafeng Pan, et al.
Published: (2023-01-01)

Identification and validation of a costimulatory molecule-related signature to predict the prognosis for uveal melanoma patients
by: Minyao Zhao, et al.
Published: (2024-04-01)

The effect of edible bird's nests on the expression of MHC-II and costimulatory molecules of C57BL/6 mouse splenocytes
by: Theerawat Dobutr, et al.
Published: (2023-09-01)

Kinetic Changes in B7 Costimulatory Molecules and IRF4 Expression in Human Dendritic Cells during LPS Exposure
by: Henry Velazquez-Soto, et al.
Published: (2022-07-01)

Immune response induced by hematoporphyrin derivatives mediated photodynamic therapy: Immunogenic cell death and elevated costimulatory molecules
by: Shan Long, et al.
Published: (2022-07-01)

Differential expression of the costimulatory molecules CD86, CD28, CD152 and PD-1 correlates with the host-parasite outcome in leprosy
by: Maria de Lourdes Palermo, et al.
Published: (2012-12-01)

Anti-leukemia effect of B7 gene-modified leukemia cell-derived exosomes
by: ZHANG Difan, et al.
Published: (2025-02-01)

Targeting Costimulatory Pathways in Systemic Sclerosis
by: Gonçalo Boleto, et al.
Published: (2018-12-01)

A hexamerization-enhanced, Fc-silenced agonistic CD27 antibody amplifies T-cell effector functions as single agent and in combination with PD-1 blockade
by: Işıl Altıntaş, et al.
Published: (2025-07-01)

Diagnostic significance of soluble adhesion molecules and costimulatory molecules of immune cells in the patients with ischemic heart disease
by: A. V. Logatkina, et al.
Published: (2020-01-01)

Integrating machine learning algorithms and multiple immunohistochemistry validation to unveil novel diagnostic markers based on costimulatory molecules for predicting immune microenvironment status in triple-negative breast cancer
by: Chao Zhang, et al.
Published: (2024-06-01)

Expression of costimulatory molecule CD70 is prognostic in small cell lung cancer
by: David Dora, et al.
Published: (2025-04-01)

A flexible liposomal polymer complex as a platform of specific and regulable immune regulation for individual cancer immunotherapy
by: Chia-Hung Chen, et al.
Published: (2023-01-01)

A novel costimulatory molecule gene-modified leukemia cell-derived exosome-targeted CD4+ T cell vaccine efficiently enhances anti-leukemia immunity
by: Jiaqi Li, et al.
Published: (2022-11-01)

Small-molecule inhibitors of the CD40–CD40L costimulatory interaction are effective in pancreatic islet transplantation and prevention of type 1 diabetes models
by: Sung-Ting Chuang, et al.
Published: (2024-11-01)

Cladribine Alters Immune Cell Surface Molecules for Adhesion and Costimulation: Further Insights to the Mode of Action in Multiple Sclerosis
by: Tobias Moser, et al.
Published: (2021-11-01)

MOLECULAR MECHANISMS OF DEACTIVATION OF DENDRITIC CELLS IN PATIENTS WITH PULMONARY TUBERCULOSIS
by: Z. K. Khaitova
Published: (2013-02-01)

In Silico Evaluation of HN-N07 Small Molecule as an Inhibitor of Angiogenesis and Lymphangiogenesis Oncogenic Signatures in Non-Small Cell Lung Cancer
by: Lung-Ching Chen, et al.
Published: (2023-07-01)

Minimalistic In Vitro Culture to Drive Human Naive B Cell Differentiation into Antibody-Secreting Cells
by: Peter-Paul A. Unger, et al.
Published: (2021-05-01)

A tumor microenvironment gene set–Based prognostic signature for non-small-cell lung cancer
by: Yingsheng Wen, et al.
Published: (2022-08-01)

Clinical Effect of Treatment with Metformin for Type 2 Diabetes on Non-Small Cell Lung Cancer Patients Undergoing Immunotherapy: A Retrospective Study
by: Wang Y, et al.
Published: (2024-12-01)

Sex difference in response to non-small cell lung cancer immunotherapy: an updated meta-analysis
by: Jiali Liang, et al.
Published: (2022-12-01)

Clinical and prognostic significance of T-regulatory cells and CD28 expression on T-lymphocytes in patients with immune thrombocytopenia
by: Yu. Yu. Chuksina, et al.
Published: (2024-12-01)

Activation of OX40 and CD27 Costimulatory Signalling in Sheep through Recombinant Ovine Ligands
by: José Manuel Rojas, et al.
Published: (2020-06-01)

Small molecule innate immune modulators in cancer therapy
by: Avijit Goswami, et al.
Published: (2024-09-01)

T Cell Invigoration is Associated with the Clinical Response to Anti-PD-1-Based Immunotherapy in Non-Small Cell Lung Cancer
by: Wu H, et al.
Published: (2023-10-01)

Effects of lung cancer cell-associated B7-H1 on T-cell proliferation in vitro and in vivo
by: K. Chen, et al.
Published: (2016-06-01)

Impact of duration of maintenance immunotherapy on the prognosis of locally advanced non-small cell lung cancer treated with chemoradiotherapy
by: HuiQi Fan, et al.
Published: (2025-07-01)

Identification of disulfidptosis-related subgroups and prognostic signatures in lung adenocarcinoma using machine learning and experimental validation
by: Yuzhi Wang, et al.
Published: (2023-09-01)

ICOS and OX40 tandem co-stimulation enhances CAR T-cell cytotoxicity and promotes T-cell persistence phenotype
by: Eider Moreno-Cortes, et al.
Published: (2023-08-01)

Prognostic significance of CD276 in non-small cell lung cancer
by: Zhang Changgong, et al.
Published: (2019-11-01)

Small molecule-based immunomodulators for cancer therapy
by: Yinrong Wu, et al.
Published: (2022-12-01)

Immunological Characteristics of Hepatic Dendritic Cells in Patients and Mouse Model with Liver <i>Echinococcus multilocularis</i> Infection
by: Hui Wang, et al.
Published: (2024-04-01)

Predictive factors for progression‐free survival in non‐small cell lung cancer patients receiving nivolumab based on performance status
by: Yuichi Adachi, et al.
Published: (2020-02-01)

Costimulatory Function of Cd58/Cd2 Interaction in Adaptive Humoral Immunity in a Zebrafish Model
by: Tong Shao, et al.
Published: (2018-05-01)

Radiofrequency ablation for stage <IIB non‐small cell lung cancer: Opportunities, challenges, and the road ahead
by: Qing Zhao, et al.
Published: (2023-11-01)

Identification of a coagulation‐related signature correlated with immune infiltration and their prognostic implications in lung adenocarcinoma
by: Siqian Yang, et al.
Published: (2023-11-01)