State of play in the molecular presentation and recognition of anti-tumor lipid-based analogues

The Natural Killer T cells (NKT) are a unique subset of T lymphocytes that recognize lipid-based antigens that are presented by the monomorphic MHC-I-like molecule, CD1d. Over 30 years ago, the discovery of the glycolipid α-Galactosylceramide (α-GalCer) from the marine sponge Agelas mauritianus, as...

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Bibliographic Details
Published in:	Frontiers in Immunology
Main Authors:	T. Praveena, Jérôme Le Nours
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2024-11-01
Subjects:	CD1d glycolipids iNKT cells α-GalCer tumor immunotherapy
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2024.1479382/full

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