Use of activated enol ethers in the synthesis of pyrazoles: reactions with hydrazine and a study of pyrazole tautomerism

Activated enol ethers derived from esters or the dinitrile of malonic acid, or from pentane-2,4-dione were treated with hydrazine hydrate. The structures of the obtained products – pyrazoles 5 – were studied with a focus on tautomerism and supramolecular structure. A reverse addition of the reagents...

وصف كامل

التفاصيل البيبلوغرافية
الحاوية / القاعدة:Beilstein Journal of Organic Chemistry
المؤلفون الرئيسيون: Denisa Tarabová, Stanislava Šoralová, Martin Breza, Marek Fronc, Wolfgang Holzer, Viktor Milata
التنسيق: مقال
اللغة:الإنجليزية
منشور في: Beilstein-Institut 2014-04-01
الموضوعات:
bis-enehydrazines
enol ethers
NMR
pyrazole
tautomerism
الوصول للمادة أونلاين:https://doi.org/10.3762/bjoc.10.70
الوصف
الملخص:Activated enol ethers derived from esters or the dinitrile of malonic acid, or from pentane-2,4-dione were treated with hydrazine hydrate. The structures of the obtained products – pyrazoles 5 – were studied with a focus on tautomerism and supramolecular structure. A reverse addition of the reagents led to the isolation of two novel products, namely bis-enehydrazines 6 with an unsymmetrical arrangement of the formally equivalent subunits.
تدمد:1860-5397

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