The Role of Inflammasome-Dependent and Inflammasome-Independent NLRP3 in the Kidney

Cytoplasmic nucleotide-binding oligomerization domain-like receptor protein 3 (NLRP3) forms an inflammasome with apoptosis-associated speck-like protein containing a CARD (ASC) and pro-caspase-1, which is followed by the cleavage of pro-caspase-1 to active caspase-1 and ultimately the activation of...

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Bibliographic Details
Published in:	Cells
Main Authors:	Yang Gyun Kim, Su-Mi Kim, Ki-Pyo Kim, Sang-Ho Lee, Ju-Young Moon
Format:	Article
Language:	English
Published:	MDPI AG 2019-11-01
Subjects:	nlrp3 inflammasome kidney nlrp3 inhibitor
Online Access:	https://www.mdpi.com/2073-4409/8/11/1389

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