Pathology identifies glomerular treatment targets in diabetic nephropathy

The development of the glomerular injury in diabetic nephropathy involves interactions between podocytes, endothelium, and the mesangium. Loss of podocytes is an early and critical step in the development of diabetic nephropathy, and analysis of structural lesions within the mesangium such as mesang...

Full description

Bibliographic Details
Published in:	Kidney Research and Clinical Practice
Main Authors:	Charles E. Alpers, Kelly L. Hudkins
Format:	Article
Language:	English
Published:	The Korean Society of Nephrology 2018-06-01
Subjects:	Diabetic nephropathies Histology Pathology Podocytes
Online Access:	https://doi.org/10.23876/j.krcp.2018.37.2.106

Similar Items

Podocyte Pathology and Nephropathy
by: Sandra eMerscher, et al.
Published: (2014-07-01)

Effects of autophagy in the process of diabetic nephropathy
by: LIU Nan, et al.
Published: (2015-01-01)

Artificial intelligence assists identification and pathologic classification of glomerular lesions in patients with diabetic nephropathy
by: Qunjuan Lei, et al.
Published: (2024-04-01)

Puerarin Attenuates Diabetic Nephropathy by Promoting Autophagy in Podocytes
by: Xueling Li, et al.
Published: (2020-02-01)

Tacrolimus repairs glomerular podocytes injury in rats with adriamycin induced nephropathy
by: CHEN Cai-ming, et al.
Published: (2020-01-01)

Membranous nephropathy: Clearer pathology and mechanisms identify potential strategies for treatment
by: Edmund Y. M. Chung, et al.
Published: (2022-11-01)

Use and isolation of urinary exosomes as biomarkers for diabetic nephropathy
by: Luca eMusante, et al.
Published: (2014-09-01)

Effects of dapagliflozin on podocyte damage and oxidative stress in patients with diabetic nephropathy
by: Yajing Shi, et al.
Published: (2025-08-01)

NUP160 knockdown inhibits the progression of diabetic nephropathy in vitro and in vivo
by: Jiayong Xie, et al.
Published: (2022-12-01)

The role of sirolimus in proteinuria in diabetic nephropathy rats
by: JinJun Wang, et al.
Published: (2017-12-01)

Scutellarin ameliorates diabetic nephropathy via TGF-β1 signaling pathway
by: Bangrui Huang, et al.
Published: (2024-04-01)

Screening and Identification of Novel DNA Aptamer for Targeted Delivery to Injured Podocytes in Glomerular Diseases
by: Chao Zhou, et al.
Published: (2025-05-01)

Targeting ferroptosis as a prospective therapeutic approach for diabetic nephropathy
by: Qinrui Wu, et al.
Published: (2024-12-01)

Renalase protects against podocyte injury by inhibiting oxidative stress and apoptosis in diabetic nephropathy
by: Wu Yiru, et al.
Published: (2024-11-01)

Metformin improves diabetic kidney disease
by: Beladi Mousavi Seyed Seifollah, et al.
Published: (2012-01-01)

Novel thinking of renal pathology on the diagnosis and prognosis of diabetic nephropathy
by: Zhou Ting, et al.
Published: (2021-01-01)

Epigenetic Alterations in Podocytes in Diabetic Nephropathy
by: Erina Sugita, et al.
Published: (2021-09-01)

Breviscapine alleviates podocyte injury by inhibiting NF-κB/NLRP3-mediated pyroptosis in diabetic nephropathy
by: Linlin Sun, et al.
Published: (2023-02-01)

Flavonoids on diabetic nephropathy: advances and therapeutic opportunities
by: Qichao Hu, et al.
Published: (2021-08-01)

Complement Activation in Patients With Diabetic Nephropathy
by: Pascal Bus, et al.
Published: (2018-03-01)

Histological changes of kidney in diabetic nephropathy
by: Mohsen pourghasem, et al.
Published: (2015-07-01)

Treatment of Membranous Nephropathy by Disulfiram through Inhibition of Podocyte Pyroptosis
by: Daoyuan Lv, et al.
Published: (2022-05-01)

The Wnt Signaling Pathway in Diabetic Nephropathy
by: Haiying Wang, et al.
Published: (2022-01-01)

Piperazine ferulate inhibits diabetic nephropathy by suppressing AGE/RAGE-mediated inflammatory signaling in rats and podocytes
by: Xiu-Meng Zhang, et al.
Published: (2024-08-01)

The protective effects of rapamycin on cell autophagy in the renal tissues of rats with diabetic nephropathy via mTOR-S6K1-LC3II signaling pathway
by: Lei Liu, et al.
Published: (2018-10-01)

ATF4-dependent heme-oxygenase-1 attenuates diabetic nephropathy by inducing autophagy and inhibiting apoptosis in podocyte
by: Shizhu Yuan, et al.
Published: (2021-01-01)

G protein-coupled receptor 107 deficiency promotes development of diabetic nephropathy
by: Deping Xu, et al.
Published: (2025-02-01)

Sirt6 overexpression relieves ferroptosis and delays the progression of diabetic nephropathy via Nrf2/GPX4 pathway
by: Lingyu Du, et al.
Published: (2024-12-01)

Protective effects of specneuzhenide on renal injury in rats with diabetic nephropathy
by: Yin Jiangning, et al.
Published: (2019-10-01)

mRNA Expression of Podocyte Associated Proteins in Peripheral Blood Mononuclear Cells of Type 2 Diabetes Mellitus Patients with and without Nephropathy
by: Gouri M. Bhoite, et al.
Published: (2020-07-01)

Combined Melatonin and Extracorporeal Shock Wave Therapy Enhances Podocyte Protection and Ameliorates Kidney Function in a Diabetic Nephropathy Rat Model
by: Chang-Chun Hsiao, et al.
Published: (2021-05-01)

Renal Protective Effect of Boeravinone B against Diabetic Nephropathy Rats via Inhibition of The Inflammatory and JAK2/STAT3 Signalling Pathway
by: Wenbin Wen, et al.
Published: (2024-06-01)

Pathological validation of the Japanese Renal Pathology Society classification and challenges in predicting renal prognosis in patients with diabetic nephropathy
by: Taeyeong Kim, et al.
Published: (2022-09-01)

tBHQ attenuates podocyte injury in diabetic nephropathy by inhibiting NADPH oxidase-derived ROS generation via the Nrf2/HO-1 signalling pathway
by: Ting Liu, et al.
Published: (2022-09-01)

Astaxanthin attenuates diabetic kidney injury through upregulation of autophagy in podocytes and pathological crosstalk with mesangial cells
by: Mengqi Hong, et al.
Published: (2024-12-01)

Zuogui Wan ameliorates high glucose-induced podocyte apoptosis and improves diabetic nephropathy in db/db mice
by: Bingbing Zhu, et al.
Published: (2022-11-01)

Protective effect of GLP-1 analog liraglutide on podocytes in mice with diabetic nephropathy
by: Shaomin Shi, et al.
Published: (2023-09-01)

Long noncoding RNA MEG3 suppresses podocyte injury in diabetic nephropathy by inactivating Wnt/β-catenin signaling
by: Xiajing Che, et al.
Published: (2019-11-01)

HNRNP I promotes IRAK1 degradation to reduce podocyte apoptosis and inflammatory response alleviating renal injury in diabetic nephropathy
by: Zichen Rao, et al.
Published: (2024-09-01)

Correlation of renal pathological changes with survival and prognosis in patients with diabetic nephropathy
by: TAN Xiao-yan, et al.
Published: (2019-01-01)