Structural and functional correlates of epileptogenesis — Does gender matter?

In the majority of neuropsychiatric conditions, marked gender-based differences have been found in the epidemiology, clinical manifestations, and therapy of disease. One possible reason is that sex differences in cerebral morphology, structural and functional connections, render men and women differ...

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Bibliographic Details
Published in:Neurobiology of Disease
Main Authors: Ivanka Savic, Jerome Engel, Jr.
Format: Article
Language:English
Published: Elsevier 2014-10-01
Subjects:
Seizures
Cerebral connectivity
MRI
MTLE
Sex difference
Generalized epilepsy
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996114001466
Description
Summary:In the majority of neuropsychiatric conditions, marked gender-based differences have been found in the epidemiology, clinical manifestations, and therapy of disease. One possible reason is that sex differences in cerebral morphology, structural and functional connections, render men and women differentially vulnerable to various disease processes. The present review addresses this issue with respect to the functional and structural correlates to some forms of epilepsy.
ISSN:1095-953X

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