Protective Potential of Sodium-Glucose Cotransporter 2 Inhibitors in Internal Medicine (Part 1)

Sodium-glucose cotransporter 2 inhibitors (SGLT2i) have emerged as a revolutionary class of drugs with far-reaching protective effects in multiple organs. The protective potential of SGLT2i is much broader than that of the classical concept of glucose control and consists of an entire conglomerate o...

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Bibliographic Details
Published in:Инновационная медицина Кубани
Main Authors: A. A. Avagimyan, M. Sheibani, A. I. Trofimenko, E. E. Lysov, F. M. Khamidova, A. Z. Aznauryan, L. M. Sukiasyan, K. T. Sahakyan, T. R. Gevorgyan, M. R. Tatoyan, G. L. Mkrtchyan, G. L. Meltonyan, A. R. Petrosyan, L. A. Martemyanova, R. R. Petrosyan, O. I. Urazova, N. V. Pogosova, N. Sarrafzadegan
Format: Article
Language:English
Published: Scientific Research Institute, Ochapovsky Regional Clinical Hospital no. 1 2024-11-01
Subjects:
sglt2i
cardioprotection
nephroprotection
dapagliflozin
empagliflozin
Online Access:https://www.innovmedkub.ru/jour/article/view/979
Description
Summary:Sodium-glucose cotransporter 2 inhibitors (SGLT2i) have emerged as a revolutionary class of drugs with far-reaching protective effects in multiple organs. The protective potential of SGLT2i is much broader than that of the classical concept of glucose control and consists of an entire conglomerate of associated pleiotropic effects. This study aims to provide a descriptive review of the pleiotropic therapeutic potential of SGLT2i. The first part of the literature review examined the use of SGLT2i in cardiology and nephrology. The use of SGLT2i represents an innovative approach to improving patients’ quality of life and course of heart failure and chronic kidney disease, regardless of left ventricular ejection fraction and type 2 diabetes.
ISSN:2541-9897

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