Hot-Melt Extrusion as an Effective Technique for Obtaining an Amorphous System of Curcumin and Piperine with Improved Properties Essential for Their Better Biological Activities

Poor bioavailability hampers the use of curcumin and piperine as biologically active agents. It can be improved by enhancing the solubility as well as by using bioenhancers to inhibit metabolic transformation processes. Obtaining an amorphous system of curcumin and piperine can lead to the overcomin...

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Bibliographic Details
Published in:	Molecules
Main Authors:	Kamil Wdowiak, Robert Pietrzak, Ewa Tykarska, Judyta Cielecka-Piontek
Format:	Article
Language:	English
Published:	MDPI AG 2023-05-01
Subjects:	amorphous systems curcumin piperine hot-melt extrusion bioaccessibility delivery system
Online Access:	https://www.mdpi.com/1420-3049/28/9/3848

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