Automated Liquid Handling Extraction and Rapid Quantification of Underivatized Amino Acids and Tryptophan Metabolites from Human Serum and Plasma Using Dual-Column U(H)PLC-MRM-MS and Its Application to Prostate Cancer Study

Amino acids (AAs) and their metabolites are important building blocks, energy sources, and signaling molecules associated with various pathological phenotypes. The quantification of AA and tryptophan (TRP) metabolites in human serum and plasma is therefore of great diagnostic interest. Therefore, ro...

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Bibliographic Details
Published in:	Metabolites
Main Authors:	Tobias Kipura, Madlen Hotze, Alexa Hofer, Anna-Sophia Egger, Lea E. Timpen, Christiane A. Opitz, Paul A. Townsend, Lee A. Gethings, Kathrin Thedieck, Marcel Kwiatkowski
Format:	Article
Language:	English
Published:	MDPI AG 2024-06-01
Subjects:	amino acids tryptophan metabolites analysis automation LC-MS mixed-mode chromatography prostate cancer
Online Access:	https://www.mdpi.com/2218-1989/14/7/370

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