Excitatory neurons are more disinhibited than inhibitory neurons by chloride dysregulation in the spinal dorsal horn

Neuropathic pain is a debilitating condition caused by the abnormal processing of somatosensory input. Synaptic inhibition in the spinal dorsal horn plays a key role in that processing. Mechanical allodynia – the misperception of light touch as painful – occurs when inhibition is compromised. Disinh...

وصف كامل

التفاصيل البيبلوغرافية
الحاوية / القاعدة:eLife
المؤلفون الرئيسيون: Kwan Yeop Lee, Stéphanie Ratté, Steven A Prescott
التنسيق: مقال
اللغة:الإنجليزية
منشور في: eLife Sciences Publications Ltd 2019-11-01
الموضوعات:
allodynia
neuropathic pain
disinhibition
spinal cord
KCC2
spatial summation
الوصول للمادة أونلاين:https://elifesciences.org/articles/49753

الانترنت

https://elifesciences.org/articles/49753

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