Piracetam-induced neuroprotection in lipopolysaccharides-challenged EOC-20 cells and mouse brain via attenuating oxidative stress
Abstract Therapeutically, piracetam has been used for decades as a cognitive enhancer for memory- related neuronal disorders. The present study aimed to investigate the neuroprotective potential of piracetam on lipopolysaccharides (LPS)-induced neuronal deficit using both in-vitro and in-vivo experi...
| Published in: | Brazilian Journal of Pharmaceutical Sciences |
|---|---|
| Main Author: | Vasudevan Mani |
| Format: | Article |
| Language: | English |
| Published: |
Universidade de São Paulo
2023-01-01
|
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502022000100309&tlng=en |
Similar Items
Piracetam as a Therapeutic Agent for Doxorubicin-Induced Cognitive Deficits by Enhancing Cholinergic Functions and Reducing Neuronal Inflammation, Apoptosis, and Oxidative Stress in Rats
by: Vasudevan Mani, et al.
Published: (2022-12-01)
by: Vasudevan Mani, et al.
Published: (2022-12-01)
Synergistic neurotrophic effects of piracetam and thiotriazoline
by: O. A. Gromova, et al.
Published: (2016-03-01)
by: O. A. Gromova, et al.
Published: (2016-03-01)
Oral Piracetam in Patients with Chronic Vertigo
by: Özgür Akdoğan, et al.
Published: (2003-09-01)
by: Özgür Akdoğan, et al.
Published: (2003-09-01)
Neuroprotective Effect of Piracetam against Cocaine-Induced Neuro Epigenetic Modification of DNA Methylation in Astrocytes
by: Kalaiselvi Sivalingam, et al.
Published: (2020-09-01)
by: Kalaiselvi Sivalingam, et al.
Published: (2020-09-01)
A Comparative Study of the Prescription of Memantine and Piracetam in Poststroke Aphasia
by: Fariborz Khorvash, et al.
Published: (2015-12-01)
by: Fariborz Khorvash, et al.
Published: (2015-12-01)
Synergy of piracetam and aminalon in the cerebroprotective effect of olatropyl.
by: V. I. Mamchur, et al.
Published: (2018-11-01)
by: V. I. Mamchur, et al.
Published: (2018-11-01)
Neurobehavioral Impacts of Xylazine and Piracetam Interaction on NADH Oxidase in the Rat Brain
by: Shaker M. Kermasha, et al.
Published: (2024-12-01)
by: Shaker M. Kermasha, et al.
Published: (2024-12-01)
Investigation of the Formation Process of Two Piracetam Cocrystals during Grinding
by: Keith Gordon, et al.
Published: (2011-10-01)
by: Keith Gordon, et al.
Published: (2011-10-01)
Elucidating the Three‐Dimensional Structure of Piracetam through Rotational Spectroscopy
by: S. Mato, et al.
Published: (2025-08-01)
by: S. Mato, et al.
Published: (2025-08-01)
„Cognitive Enhancement" or non-evidence-based nootropic abuse? – Use of Piracetam in Hungary
by: András Érszegi, et al.
Published: (2024-04-01)
by: András Érszegi, et al.
Published: (2024-04-01)
The Effect of Piracetam against Acetyl Choline (Ach) In Behavioral Changes with Some Biochemical Parameters in Adult Mice
by: Bassam Al-Shimmary, et al.
Published: (2017-12-01)
by: Bassam Al-Shimmary, et al.
Published: (2017-12-01)
Invasive epithelial ovarian carcinoma (EOC) at a young age: role of fertility-sparing
by: Puja Agung Antonius, et al.
Published: (2022-05-01)
by: Puja Agung Antonius, et al.
Published: (2022-05-01)
The Effect of Piracetam Administration on Cerebral Palsy Prevention in Rat Fetuses Born To Pregnant Rats by Determining Bdnf Levels in Brain Tissue
by: Dudy Aldiansyah, et al.
Published: (2024-12-01)
by: Dudy Aldiansyah, et al.
Published: (2024-12-01)
Environmental sustainability profiles assessment of HPLC stability indicating method for quantitation of piracetam and vincamine in pharmaceutical medications
by: Samya Sh. Alenezi, et al.
Published: (2025-08-01)
by: Samya Sh. Alenezi, et al.
Published: (2025-08-01)
Experimental substantiation of the expediency of the combined use of piracetam and metformin for pharmacological correction of cognitive disorders in conditions of prolonged hyperglycemia
by: А. E. Lievykh, et al.
Published: (2020-10-01)
by: А. E. Lievykh, et al.
Published: (2020-10-01)
Development and Preclinical Evaluation of Fixed-Dose Capsules Containing Nicergoline, Piracetam, and Hawthorn Extract for Sensorineural Hearing Loss
by: Lucia Maria Rus, et al.
Published: (2025-08-01)
by: Lucia Maria Rus, et al.
Published: (2025-08-01)
Neuroprotection by Skimmianine in Lipopolysaccharide-Activated BV-2 Microglia
by: Folashade A. Ogunrinade, et al.
Published: (2023-01-01)
by: Folashade A. Ogunrinade, et al.
Published: (2023-01-01)
The Effect of Priacetam in Aphasia due to Acute Brain Ischemic Stroke: Clinical trial
by: A Hamzei-Moghaddam, et al.
Published: (2014-06-01)
by: A Hamzei-Moghaddam, et al.
Published: (2014-06-01)
The influence of Piracetam and Phenotropil on brain dopamine and serotonin metabolism in CD-1 mice sub-populations, diverging in attention sustainability
by: N. A. Sukhorukova, et al.
Published: (2022-02-01)
by: N. A. Sukhorukova, et al.
Published: (2022-02-01)
Exosomes released from M2 macrophages transfer miR‐221‐3p contributed to EOC progression through targeting CDKN1B
by: Xiaoduan Li, et al.
Published: (2020-08-01)
by: Xiaoduan Li, et al.
Published: (2020-08-01)
Neuroprotective Potential of Flavonoids in Brain Disorders
by: Syed Hasan, et al.
Published: (2023-08-01)
by: Syed Hasan, et al.
Published: (2023-08-01)
Dielectric Performance of Silica-Filled Nanocomposites Based on Miscible (PP/PP-HI) and Immiscible (PP/EOC) Polymer Blends
by: Xiaozhen He, et al.
Published: (2021-01-01)
by: Xiaozhen He, et al.
Published: (2021-01-01)
Comparative pharmacokinetics and pharmacodinamics of noopept, its activity metabolite cycloprolylglycine and piracetam
by: Svetlana Boyko, et al.
Published: (2019-09-01)
by: Svetlana Boyko, et al.
Published: (2019-09-01)
Efficacy and safety of compound porcine cerebroside and ganglioside injection (CPCGI) versus piracetam on cognition and functional outcomes for adults with traumatic brain injury: A study protocol for randomized controlled trial
by: Tao Liu, et al.
Published: (2024-09-01)
by: Tao Liu, et al.
Published: (2024-09-01)
Icariin attenuates neuroinflammation and exerts dopamine neuroprotection via an Nrf2-dependent manner
by: Bei Zhang, et al.
Published: (2019-04-01)
by: Bei Zhang, et al.
Published: (2019-04-01)
Betahistine’s Neuroprotective Actions against Lipopolysaccharide-Induced Neurotoxicity: Insights from Experimental and Computational Studies
by: Vasudevan Mani, et al.
Published: (2024-08-01)
by: Vasudevan Mani, et al.
Published: (2024-08-01)
Selective COX-2 Inhibitors as Neuroprotective Agents in Traumatic Brain Injury
by: Matthew I. Hiskens, et al.
Published: (2024-08-01)
by: Matthew I. Hiskens, et al.
Published: (2024-08-01)
Curcumin-Piperlongumine Hybrids with a Multitarget Profile Elicit Neuroprotection in In Vitro Models of Oxidative Stress and Hyperphosphorylation
by: Ángel Cores, et al.
Published: (2021-12-01)
by: Ángel Cores, et al.
Published: (2021-12-01)
Cannabidiol's neuroprotective properties and potential treatment of traumatic brain injuries
by: Mackenzie M. Aychman, et al.
Published: (2023-02-01)
by: Mackenzie M. Aychman, et al.
Published: (2023-02-01)
Elucidating the pivotal molecular mechanisms, therapeutic and neuroprotective effects of lithium in traumatic brain injury
by: Seidu A. Richard
Published: (2024-06-01)
by: Seidu A. Richard
Published: (2024-06-01)
Development of quantitative structure activity relationships (QSARs) for predicting the aggregation of TiO2 nanoparticles under favorable conditions
by: Jaewoong Lee
Published: (2024-04-01)
by: Jaewoong Lee
Published: (2024-04-01)
Trehalose: Neuroprotective Effects and Mechanisms—An Updated Review
by: Borislav Sevriev, et al.
Published: (2024-10-01)
by: Borislav Sevriev, et al.
Published: (2024-10-01)
Hibiscetin attenuates oxidative, nitrative stress and neuroinflammation via suppression of TNF-α signaling in rotenone induced parkinsonism in rats
by: Sami I. Alzarea, et al.
Published: (2022-12-01)
by: Sami I. Alzarea, et al.
Published: (2022-12-01)
Moss Extracts as Natural Neuroprotective Agents: Mitigating LPS-Induced Neuroinflammation and Microglial Activation
by: Tijana D. Stojanović, et al.
Published: (2025-05-01)
by: Tijana D. Stojanović, et al.
Published: (2025-05-01)
Isolation, Characterization and Neuroprotective Activity of Folecitin: An In Vivo Study
by: Umar Farooq, et al.
Published: (2021-08-01)
by: Umar Farooq, et al.
Published: (2021-08-01)
Vertigo in neurological practice (common problems of diagnosis and treatment)
by: Olga Vladimirovna Kosivtsova, et al.
Published: (2012-03-01)
by: Olga Vladimirovna Kosivtsova, et al.
Published: (2012-03-01)
Assessment of the prevalence of nootropic drugs by elderly patients in geriatric practice
by: Emilia Główczewska-Siedlecka, et al.
Published: (2017-08-01)
by: Emilia Główczewska-Siedlecka, et al.
Published: (2017-08-01)
Current state of neuroprotective therapy using antibiotics in human traumatic brain injury and animal models
by: Katharina Ritter, et al.
Published: (2024-02-01)
by: Katharina Ritter, et al.
Published: (2024-02-01)
Neuroprotective Effects of Berberine After Severe Traumatic Brain Injury in Male Rats: The Role of IL-1β and IL 10
by: Siavash Anbai, et al.
Published: (2022-01-01)
by: Siavash Anbai, et al.
Published: (2022-01-01)
Probiotic treatment induces sex-dependent neuroprotection and gut microbiome shifts after traumatic brain injury
by: Morgan Holcomb, et al.
Published: (2025-04-01)
by: Morgan Holcomb, et al.
Published: (2025-04-01)
Similar Items
-
Piracetam as a Therapeutic Agent for Doxorubicin-Induced Cognitive Deficits by Enhancing Cholinergic Functions and Reducing Neuronal Inflammation, Apoptosis, and Oxidative Stress in Rats
by: Vasudevan Mani, et al.
Published: (2022-12-01) -
Synergistic neurotrophic effects of piracetam and thiotriazoline
by: O. A. Gromova, et al.
Published: (2016-03-01) -
Oral Piracetam in Patients with Chronic Vertigo
by: Özgür Akdoğan, et al.
Published: (2003-09-01) -
Neuroprotective Effect of Piracetam against Cocaine-Induced Neuro Epigenetic Modification of DNA Methylation in Astrocytes
by: Kalaiselvi Sivalingam, et al.
Published: (2020-09-01) -
A Comparative Study of the Prescription of Memantine and Piracetam in Poststroke Aphasia
by: Fariborz Khorvash, et al.
Published: (2015-12-01)
