Occurrence and Dietary Exposure to Acrylamide from Foods Consumed within and outside Main Meals in Singapore
This study investigated the influence of ‘snackification’ in Singaporean diets, leading to increased dietary acrylamide exposure. Acrylamide concentrations in commonly consumed foods within and outside the main meals were measured using liquid chromatography with tandem mass spectrometry (LC-MS/MS)....
| 出版年: | Foods |
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| 主要な著者: | , , , , , , , , , , , , , |
| フォーマット: | 論文 |
| 言語: | 英語 |
| 出版事項: |
MDPI AG
2023-08-01
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| 主題: | |
| オンライン・アクセス: | https://www.mdpi.com/2304-8158/12/16/3022 |
| _version_ | 1850397660833382400 |
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| author | Wesley Zongrong Yu Ping Shen Ignatius Lim Raymond Rong Sheng Shi Miaohua Cai Yee Soon Chin Ai Jin Tay Wei Min Ang Jun Cheng Er Geraldine Songlen Lim Yuansheng Wu Angela Li Kyaw Thu Aung Sheot Harn Chan |
| author_facet | Wesley Zongrong Yu Ping Shen Ignatius Lim Raymond Rong Sheng Shi Miaohua Cai Yee Soon Chin Ai Jin Tay Wei Min Ang Jun Cheng Er Geraldine Songlen Lim Yuansheng Wu Angela Li Kyaw Thu Aung Sheot Harn Chan |
| author_sort | Wesley Zongrong Yu |
| collection | DOAJ |
| container_title | Foods |
| description | This study investigated the influence of ‘snackification’ in Singaporean diets, leading to increased dietary acrylamide exposure. Acrylamide concentrations in commonly consumed foods within and outside the main meals were measured using liquid chromatography with tandem mass spectrometry (LC-MS/MS). High acrylamide concentrations were detected in vegetables cooked at high temperatures (ranging from 0.5 to 478.4 µg/kg) and potato-based crackers and chips (ranging from 81.8 to 2095.8 µg/kg). The estimated total dietary exposure for the Singapore population was 0.165 µg/kg bw/day for general consumers and 0.392 µg/kg bw/day for high consumers (95th percentile). The acrylamide exposure from outside main meals was nearly equivalent to that from within the main meals. The calculated margins of exposure (MOE) were below 10,000, indicating potential human health concern. These findings highlight the need for industry practices and consumer advisories to reduce acrylamide exposure from foods consumed both within and outside main meals. |
| format | Article |
| id | doaj-art-582ee151bbf548b3b8bb33f9165aa9aa |
| institution | Directory of Open Access Journals |
| issn | 2304-8158 |
| language | English |
| publishDate | 2023-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| spelling | doaj-art-582ee151bbf548b3b8bb33f9165aa9aa2025-08-19T22:51:39ZengMDPI AGFoods2304-81582023-08-011216302210.3390/foods12163022Occurrence and Dietary Exposure to Acrylamide from Foods Consumed within and outside Main Meals in SingaporeWesley Zongrong Yu0Ping Shen1Ignatius Lim2Raymond Rong Sheng Shi3Miaohua Cai4Yee Soon Chin5Ai Jin Tay6Wei Min Ang7Jun Cheng Er8Geraldine Songlen Lim9Yuansheng Wu10Angela Li11Kyaw Thu Aung12Sheot Harn Chan13National Centre for Food Science, Singapore Food Agency, 7 International Business Park, Singapore 609919, SingaporeNational Centre for Food Science, Singapore Food Agency, 7 International Business Park, Singapore 609919, SingaporeNational Centre for Food Science, Singapore Food Agency, 7 International Business Park, Singapore 609919, SingaporeNational Centre for Food Science, Singapore Food Agency, 7 International Business Park, Singapore 609919, SingaporeNational Centre for Food Science, Singapore Food Agency, 7 International Business Park, Singapore 609919, SingaporeNational Centre for Food Science, Singapore Food Agency, 7 International Business Park, Singapore 609919, SingaporeNational Centre for Food Science, Singapore Food Agency, 7 International Business Park, Singapore 609919, SingaporeNational Centre for Food Science, Singapore Food Agency, 7 International Business Park, Singapore 609919, SingaporeNational Centre for Food Science, Singapore Food Agency, 7 International Business Park, Singapore 609919, SingaporeNational Centre for Food Science, Singapore Food Agency, 7 International Business Park, Singapore 609919, SingaporeNational Centre for Food Science, Singapore Food Agency, 7 International Business Park, Singapore 609919, SingaporeNational Centre for Food Science, Singapore Food Agency, 7 International Business Park, Singapore 609919, SingaporeNational Centre for Food Science, Singapore Food Agency, 7 International Business Park, Singapore 609919, SingaporeNational Centre for Food Science, Singapore Food Agency, 7 International Business Park, Singapore 609919, SingaporeThis study investigated the influence of ‘snackification’ in Singaporean diets, leading to increased dietary acrylamide exposure. Acrylamide concentrations in commonly consumed foods within and outside the main meals were measured using liquid chromatography with tandem mass spectrometry (LC-MS/MS). High acrylamide concentrations were detected in vegetables cooked at high temperatures (ranging from 0.5 to 478.4 µg/kg) and potato-based crackers and chips (ranging from 81.8 to 2095.8 µg/kg). The estimated total dietary exposure for the Singapore population was 0.165 µg/kg bw/day for general consumers and 0.392 µg/kg bw/day for high consumers (95th percentile). The acrylamide exposure from outside main meals was nearly equivalent to that from within the main meals. The calculated margins of exposure (MOE) were below 10,000, indicating potential human health concern. These findings highlight the need for industry practices and consumer advisories to reduce acrylamide exposure from foods consumed both within and outside main meals.https://www.mdpi.com/2304-8158/12/16/3022acrylamidefoodssnackLC-MS/MSdietary exposurerisk assessment |
| spellingShingle | Wesley Zongrong Yu Ping Shen Ignatius Lim Raymond Rong Sheng Shi Miaohua Cai Yee Soon Chin Ai Jin Tay Wei Min Ang Jun Cheng Er Geraldine Songlen Lim Yuansheng Wu Angela Li Kyaw Thu Aung Sheot Harn Chan Occurrence and Dietary Exposure to Acrylamide from Foods Consumed within and outside Main Meals in Singapore acrylamide foods snack LC-MS/MS dietary exposure risk assessment |
| title | Occurrence and Dietary Exposure to Acrylamide from Foods Consumed within and outside Main Meals in Singapore |
| title_full | Occurrence and Dietary Exposure to Acrylamide from Foods Consumed within and outside Main Meals in Singapore |
| title_fullStr | Occurrence and Dietary Exposure to Acrylamide from Foods Consumed within and outside Main Meals in Singapore |
| title_full_unstemmed | Occurrence and Dietary Exposure to Acrylamide from Foods Consumed within and outside Main Meals in Singapore |
| title_short | Occurrence and Dietary Exposure to Acrylamide from Foods Consumed within and outside Main Meals in Singapore |
| title_sort | occurrence and dietary exposure to acrylamide from foods consumed within and outside main meals in singapore |
| topic | acrylamide foods snack LC-MS/MS dietary exposure risk assessment |
| url | https://www.mdpi.com/2304-8158/12/16/3022 |
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