Thioredoxin and Glutaredoxin Systems as Potential Targets for the Development of New Treatments in Friedreich’s Ataxia
The thioredoxin family consists of a small group of redox proteins present in all organisms and composed of thioredoxins (TRXs), glutaredoxins (GLRXs) and peroxiredoxins (PRDXs) which are found in the extracellular fluid, the cytoplasm, the mitochondria and in the nucleus with functions that include...
| Published in: | Antioxidants |
|---|---|
| Main Authors: | Marta Seco-Cervera, Pilar González-Cabo, Federico V. Pallardó, Carlos Romá-Mateo, José Luis García-Giménez |
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2020-12-01
|
| Subjects: | |
| Online Access: | https://www.mdpi.com/2076-3921/9/12/1257 |
Similar Items
Anesthetic Management on a Patient with Friedreichs Ataxia
by: Ulku Ozgul, et al.
Published: (2013-12-01)
by: Ulku Ozgul, et al.
Published: (2013-12-01)
Friedreich’s Ataxia with Retained Reflexes
by: J Gordon Millichap
Published: (1995-04-01)
by: J Gordon Millichap
Published: (1995-04-01)
Respiratory Function in Friedreich’s Ataxia
by: Elena Vinante, et al.
Published: (2022-08-01)
by: Elena Vinante, et al.
Published: (2022-08-01)
Involvement of Glutaredoxin and Thioredoxin Systems in the Nitrogen-Fixing Symbiosis between Legumes and Rhizobia
by: Geneviève Alloing, et al.
Published: (2018-12-01)
by: Geneviève Alloing, et al.
Published: (2018-12-01)
Genetics of Friedreich Ataxia
by: J Gordon Millichap
Published: (1997-06-01)
by: J Gordon Millichap
Published: (1997-06-01)
Analysis of Thioredoxins and Glutaredoxins in Soybean: Evidence of Translational Regulation under Water Restriction
by: María Martha Sainz, et al.
Published: (2022-08-01)
by: María Martha Sainz, et al.
Published: (2022-08-01)
Friedreichs ataxia in a diabetic patient
by: Inna Igorevna Klefortova, et al.
Published: (2010-06-01)
by: Inna Igorevna Klefortova, et al.
Published: (2010-06-01)
5-Hydroxytryptophan in Friedreich’s Ataxia
by: J Gordon Millichap
Published: (1995-06-01)
by: J Gordon Millichap
Published: (1995-06-01)
Late-Onset Friedreich’s Ataxia
by: J Gordon Millichap
Published: (1993-08-01)
by: J Gordon Millichap
Published: (1993-08-01)
Clinical and molecular studies in five Brazilian cases of Friedreich ataxia Avaliação clínica e molecular de cinco pacientes brasileiros com ataxia de Friedreich
by: IDA V.D. SCHWARTZ, et al.
Published: (1999-03-01)
by: IDA V.D. SCHWARTZ, et al.
Published: (1999-03-01)
Revisiting Friedreich's Ataxia: Phenotypic and Imaging Characteristics
by: Rohan Mahale, et al.
Published: (2024-04-01)
by: Rohan Mahale, et al.
Published: (2024-04-01)
Genetics and Friedreich Ataxia
by: J Gordon Millichap
Published: (2002-06-01)
by: J Gordon Millichap
Published: (2002-06-01)
Inducible and reversible phenotypes in a novel mouse model of Friedreich’s Ataxia
by: Vijayendran Chandran, et al.
Published: (2017-12-01)
by: Vijayendran Chandran, et al.
Published: (2017-12-01)
Friedreich's Ataxia – A Clinical Diagnosis
by: Md. Fekarul Islam, et al.
Published: (2015-01-01)
by: Md. Fekarul Islam, et al.
Published: (2015-01-01)
Iron Storage in Friedreich’s Ataxia
by: J Gordon Millichap
Published: (1999-08-01)
by: J Gordon Millichap
Published: (1999-08-01)
Clinical stage and plasma neurofilament concentration in adults with Friedreich ataxia
by: Magnus Johnsson, et al.
Published: (2024-01-01)
by: Magnus Johnsson, et al.
Published: (2024-01-01)
Friedreich’s Ataxia: dance and somatic education a case report
by: Fanny Aparecida Condé Teixeira, et al.
Published: (2018-12-01)
by: Fanny Aparecida Condé Teixeira, et al.
Published: (2018-12-01)
Anesthesia Management in Scoliosis Surgery of Patients with Friedreich’s Ataxia: A Report of Four Cases
by: Muhammed Köse, et al.
Published: (2022-12-01)
by: Muhammed Köse, et al.
Published: (2022-12-01)
Exploring neuropsychiatric symptoms in Friedreich ataxia
by: Simona Karamazovova, et al.
Published: (2024-11-01)
by: Simona Karamazovova, et al.
Published: (2024-11-01)
Long-Term Follow-Up of Friedreich Ataxia Patients
by: J Gordon Millichap
Published: (2007-05-01)
by: J Gordon Millichap
Published: (2007-05-01)
Content Validity of the Friedreich Ataxia Rating Scale in Patients with Spinocerebellar Ataxia
by: Michele Potashman, et al.
Published: (2025-01-01)
by: Michele Potashman, et al.
Published: (2025-01-01)
Spatial perspective taking is impaired in spinocerebellar ataxias and Friedreich ataxia
by: Simona Karamazovova, et al.
Published: (2025-08-01)
by: Simona Karamazovova, et al.
Published: (2025-08-01)
Friedreich’s Ataxia: A Neuronal Point of View on the Oxidative Stress Hypothesis
by: Barbara Carletti, et al.
Published: (2014-09-01)
by: Barbara Carletti, et al.
Published: (2014-09-01)
Clinical management guidelines for Friedreich ataxia: best practice in rare diseases
by: Louise A. Corben, et al.
Published: (2022-11-01)
by: Louise A. Corben, et al.
Published: (2022-11-01)
Retinal and Visual Pathways Involvement in Carriers of Friedreich’s Ataxia
by: Lucia Ziccardi, et al.
Published: (2022-12-01)
by: Lucia Ziccardi, et al.
Published: (2022-12-01)
Effectiveness of rehabilitation intervention in persons with Friedreich ataxia
by: Gabriella Paparella, et al.
Published: (2023-11-01)
by: Gabriella Paparella, et al.
Published: (2023-11-01)
Case Report: Complex cardiac arrhythmia management in the ICU for an adolescent with Friedreich ataxia
by: Oluwatomini A. Fashina, et al.
Published: (2025-04-01)
by: Oluwatomini A. Fashina, et al.
Published: (2025-04-01)
The current state of biomarker research for Friedreich’s ataxia: a report from the 2018 FARA biomarker meeting
by: Ian A Blair, et al.
Published: (2019-07-01)
by: Ian A Blair, et al.
Published: (2019-07-01)
Ferroptosis in Friedreich’s Ataxia: A Metal-Induced Neurodegenerative Disease
by: Piergiorgio La Rosa, et al.
Published: (2020-11-01)
by: Piergiorgio La Rosa, et al.
Published: (2020-11-01)
Anesthetic management in a patient with Friedreichs Ataxia: a different approach
by: Sedat Akbas, et al.
Published: (2017-03-01)
by: Sedat Akbas, et al.
Published: (2017-03-01)
Emerging antioxidant therapies in Friedreich’s ataxia
by: Fred Jonathan Edzeamey, et al.
Published: (2024-02-01)
by: Fred Jonathan Edzeamey, et al.
Published: (2024-02-01)
Abordaje en la evaluación e intervención logopédica de pacientes con ataxia de Friedreich: revisión bibliográfica
by: Silvia Moreno Escobar, et al.
Published: (2025-07-01)
by: Silvia Moreno Escobar, et al.
Published: (2025-07-01)
Improved Histone Deacetylase Inhibitors as Therapeutics for the Neurodegenerative Disease Friedreich’s Ataxia: A New Synthetic Route
by: Joel M. Gottesfeld, et al.
Published: (2011-12-01)
by: Joel M. Gottesfeld, et al.
Published: (2011-12-01)
Safety and Efficacy of The Stem Cell Transplantation in Friedreich’s Ataxia: A Report of Three Cases
by: Riza Azeri, et al.
Published: (2021-03-01)
by: Riza Azeri, et al.
Published: (2021-03-01)
A Pilot Phase 2 Randomized Trial to Evaluate the Safety and Potential Efficacy of Etravirine in Friedreich Ataxia Patients
by: Gabriella Paparella, et al.
Published: (2024-08-01)
by: Gabriella Paparella, et al.
Published: (2024-08-01)
The cognitive profile of Friedreich ataxia: a systematic review and meta-analysis
by: Gilles Naeije, et al.
Published: (2022-03-01)
by: Gilles Naeije, et al.
Published: (2022-03-01)
Oxidative Stress and Antioxidant Therapies in Friedreich’s Ataxia
by: Félix Javier Jiménez-Jiménez, et al.
Published: (2025-09-01)
by: Félix Javier Jiménez-Jiménez, et al.
Published: (2025-09-01)
Tissue Iron in Friedreich Ataxia
by: Arnulf H Koeppen
Published: (2024-01-01)
by: Arnulf H Koeppen
Published: (2024-01-01)
CARDIOMYOPATHY IN THE FRIEDREICH ATAXIA: CLINICAL PRESENTATION AND DIAGNOSTICS OF COMPLICATIONS
by: Е. I. Fomicheva, et al.
Published: (2017-11-01)
by: Е. I. Fomicheva, et al.
Published: (2017-11-01)
Impaired cross-talk between the thioredoxin and glutathione systems is related to ASK-1 mediated apoptosis in neuronal cells exposed to mercury
by: Vasco Branco, et al.
Published: (2017-10-01)
by: Vasco Branco, et al.
Published: (2017-10-01)
Similar Items
-
Anesthetic Management on a Patient with Friedreichs Ataxia
by: Ulku Ozgul, et al.
Published: (2013-12-01) -
Friedreich’s Ataxia with Retained Reflexes
by: J Gordon Millichap
Published: (1995-04-01) -
Respiratory Function in Friedreich’s Ataxia
by: Elena Vinante, et al.
Published: (2022-08-01) -
Involvement of Glutaredoxin and Thioredoxin Systems in the Nitrogen-Fixing Symbiosis between Legumes and Rhizobia
by: Geneviève Alloing, et al.
Published: (2018-12-01) -
Genetics of Friedreich Ataxia
by: J Gordon Millichap
Published: (1997-06-01)
