Immunomodulatory biomimetic nanoparticles target articular cartilage trauma after systemic administration

Post-traumatic osteoarthritis (PTOA) is one of the leading causes of disability in developed countries and accounts for 12% of all osteoarthritis cases in the United States. After trauma, inflammatory cells (macrophages amongst others) are quickly recruited within the inflamed synovium and infiltrat...

Full description

Bibliographic Details
Published in:	Heliyon
Main Authors:	Chiara Mancino, Anna Pasto, Enrica De Rosa, Luigi Dolcetti, Marco Rasponi, Patrick McCulloch, Francesca Taraballi
Format:	Article
Language:	English
Published:	Elsevier 2023-06-01
Subjects:	Posttraumatic osteoarthritis Biomimetic nanoparticles Theranostics Immunomodulation
Online Access:	http://www.sciencedirect.com/science/article/pii/S2405844023038471

Similar Items

Biomimetic Targeted Theranostic Nanoparticles for Breast Cancer Treatment
by: Suphalak Khamruang Marshall, et al.
Published: (2022-10-01)

Research progress of cartilage lubrication and biomimetic cartilage lubrication materials
by: Haoming An, et al.
Published: (2022-10-01)

Editorial: Immunomodulatory Nanomaterials in Cancer Theranostics
by: Sudip Mukherjee, et al.
Published: (2021-05-01)

“Live” Nanomaterials Process Biomimetic Recognition and Assembly In Vivo
by: Kuo Zhang, et al.
Published: (2023-11-01)

Cartilage lacuna-biomimetic hydrogel microspheres endowed with integrated biological signal boost endogenous articular cartilage regeneration
by: Hao Li, et al.
Published: (2024-11-01)

Biomimetic multizonal scaffolds for the reconstruction of zonal articular cartilage in chondral and osteochondral defects
by: Xiaoqi Lin, et al.
Published: (2025-01-01)

Advancing cancer theranostics through biomimetics: A comprehensive review
by: Kuttiappan Anitha, et al.
Published: (2024-03-01)

Strategic Design and Fabrication of Engineered Scaffolds for Articular Cartilage Repair
by: Xiongbiao Chen, et al.
Published: (2012-11-01)

Biomimetic Nanoparticles Potentiate the Anti-Inflammatory Properties of Dexamethasone and Reduce the Cytokine Storm Syndrome: An Additional Weapon against COVID-19?
by: Roberto Molinaro, et al.
Published: (2020-11-01)

Nanotechnology Biomimetic Cartilage Regenerative Scaffolds
by: Erh-Hsuin Lim, et al.
Published: (2014-05-01)

Biomimetic nanoparticles drive the mechanism understanding of shear-wave elasticity stiffness in triple negative breast cancers to predict clinical treatment
by: Dongdong Zheng, et al.
Published: (2023-04-01)

Acellular cartilage matrix biomimetic scaffold with immediate enrichment of autologous bone marrow mononuclear cells to repair articular cartilage defects
by: Litao Jia, et al.
Published: (2022-06-01)

A macrophage-like biomimetic nanoparticle with high-efficiency biofilm disruption and innate immunity activation for implant-related infection therapy
by: Guoqing Wei, et al.
Published: (2025-04-01)

Omega-3 fatty acids protect cartilage from acute injurie by reducing the mechanical sensitivity of chondrocytes
by: Fan Chen, et al.
Published: (2024-09-01)

Application of therapeutical nanoparticles with neutrophil membrane camouflaging for inflammatory plaques targeting against atherosclerosis
by: Ningnannan Zhang, et al.
Published: (2025-02-01)

Inorganic Nanoparticle-Loaded Exosomes for Biomedical Applications
by: Taraneh Barjesteh, et al.
Published: (2021-02-01)

Biomimetic Hydrogel Applications and Challenges in Bone, Cartilage, and Nerve Repair
by: Yanbing Gao, et al.
Published: (2023-09-01)

Boundary film–liquid mixed lubrication of biomimetic lubricants on cartilage interfaces
by: Dangsheng Xiong, et al.
Published: (2025-09-01)

Research on the Application of Biomimetic Design in Art and Design
by: Congrong Xiao, et al.
Published: (2025-08-01)

Longitudinal T2 Mapping and Texture Feature Analysis in the Detection and Monitoring of Experimental Post-Traumatic Cartilage Degeneration
by: Marc Sebastian Huppertz, et al.
Published: (2021-03-01)

Trends towards Biomimicry in Theranostics
by: Michael Evangelopoulos, et al.
Published: (2018-08-01)

Macrophage-biomimetic porous Se@SiO2 nanocomposites for dual modal immunotherapy against inflammatory osteolysis
by: Cheng Ding, et al.
Published: (2021-11-01)

Biomimetic gold nano-modulator for deep-tumor NIR-II photothermal immunotherapy via gaseous microenvironment remodeling strategy
by: Honglin Huang, et al.
Published: (2025-03-01)

Conditioned Serum Enhances the Chondrogenic and Immunomodulatory Behavior of Mesenchymal Stem Cells
by: Rebeca Blázquez, et al.
Published: (2019-06-01)

Articular Cartilage Regeneration in Osteoarthritis
by: Livia Roseti, et al.
Published: (2019-10-01)

Integrated biomimetic bioprinting of perichondrium with cartilage for auricle reconstruction
by: Litao Jia, et al.
Published: (2025-06-01)

Effects of Viscosupplementation on Tribological Behaviour of Articular Cartilage
by: Matúš Ranuša, et al.
Published: (2022-12-01)

Biomimetic Hybrid Systems for Tissue Engineering
by: Omid Yousefzade, et al.
Published: (2020-10-01)

Comparing the immunomodulatory properties of equine BM-MSCs culture expanded in autologous platelet lysate, pooled platelet lysate, equine serum and fetal bovine serum supplemented culture media
by: Kayla M. Even, et al.
Published: (2022-08-01)

Articular cartilage collagen: an irreplaceable framework?
by: DR Eyre, et al.
Published: (2006-11-01)

Articular cartilage collagen: an irreplaceable framework?
by: D R Eyre, et al.
Published: (2006-11-01)

Dual Protein-Based Nanocomposite Hydrogel Scaffolds Synergistically Promote Cartilage Regeneration Through Chondrocyte Differentiation and Immunomodulation
by: Huan Lei, et al.
Published: (2025-07-01)

Metal ion-crosslinking multifunctional hydrogel microspheres with inflammatory immune regulation for cartilage regeneration
by: Zhuoming Xu, et al.
Published: (2025-01-01)

Preexisting Type 1 Diabetes Mellitus Blunts the Development of Posttraumatic Osteoarthritis
by: Naiomy D Rios‐Arce, et al.
Published: (2022-05-01)

Cartilage damage involving extrusion of mineralisable matrix from the articular calcified cartilage and subchondral bone
by: A Boyde, et al.
Published: (2011-05-01)

Cartilage damage involving extrusion of mineralisable matrix from the articular calcified cartilage and subchondral bone
by: A Boyde, et al.
Published: (2011-05-01)

Challenging the Biomimetic Promise—Do Laypersons Perceive Biomimetic Buildings as More Sustainable and More Acceptable?
by: Michael Gorki, et al.
Published: (2025-02-01)

Quantitative magnetic resonance imaging of articular cartilage in osteoarthritis
by: G Blumenkrantz, et al.
Published: (2007-05-01)

Recent Advances in the Development of Biomimetic Materials
by: Maria G. Ciulla, et al.
Published: (2023-10-01)

Advancements in tissue engineering for articular cartilage regeneration
by: Maohua Chen, et al.
Published: (2024-02-01)